HAMAP rule MF_00417
General rule information
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Accession |
MF_00417 |
Dates |
19-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 25) |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=Pyrrolidone-carboxylate peptidase;
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EC 3.4.19.3;
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AltName:
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Full=5-oxoprolyl-peptidase;
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AltName:
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Full=Pyroglutamyl-peptidase I;
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Short=PGP-I;
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Short=Pyrase;
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Function |
Removes 5-oxoproline from various penultimate amino acid residues except L-proline. |
Catalytic activity |
Reaction=Release of an N-terminal pyroglutamyl group from a polypeptide, the second amino acid generally not being Pro.; EC=3.4.19.3; |
Subunit |
Homotetramer. |
Subcellular location |
Cytoplasm. |
Similarity |
Belongs to the peptidase C15 family. |
GO:0016920; Molecular function: pyroglutamyl-peptidase activity.
GO:0005737; Cellular component: cytoplasm.
From: PCP_BACAM (P46107) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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ACT_SITE
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81
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81
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E
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ACT_SITE
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144
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144
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C
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ACT_SITE
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168
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168
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H
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Additional information
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Size range |
200-222 amino acids |
Related rules |
None |
Fusion |
None |