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Annotation rule MF_00422
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General rule information [?]

Accession MF_00422
Dates 11-JUL-2001 (Created)
18-NOV-2019 (Last updated, Version 32)
Name SecE
Scope
Archaea
Bacteria
Templates D0VWU4 (SECE_AQUAE); P0AG96 (SECE_ECOLI); P35874 (SECE_THEMA); P38383 (SECE_THET8); Q57817 (SECE_METJA): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
SECE
case <OC:Bacteria>
Protein name
RecName: Full=Protein translocase subunit SecE;
else case <OC:Archaea>
Protein name
RecName: Full=Protein translocase subunit SecE;
AltName: Full=Protein transport protein Sec61 gamma subunit homolog;
end case
Gene name
secE

Comments [?]

Function Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
case <OC:Bacteria>
Subunit Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
else case <OC:Archaea>
Subunit Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
end case
case (<OC:Cyanobacteria> and not <OC:Gloeobacter>) and <Feature:Transmembrane==1>
Subcellular location Cell inner membrane; Single-pass membrane protein. Cellular thylakoid membrane; Single-pass membrane protein.
else case (<OC:Cyanobacteria> and not <OC:Gloeobacter>) and <Feature:Transmembrane>1>
Subcellular location Cell inner membrane; Multi-pass membrane protein. Cellular thylakoid membrane; Multi-pass membrane protein.
else case <OC:Gloeobacter> and <Feature:Transmembrane==1>
Subcellular location Cell inner membrane; Single-pass membrane protein.
else case <OC:Gloeobacter> and <Feature:Transmembrane>1>
Subcellular location Cell inner membrane; Multi-pass membrane protein.
else case (not defined <Property:Membrane> or <Property:Membrane=1>) and <Feature:Transmembrane==1>
Subcellular location Cell membrane; Single-pass membrane protein.
else case (not defined <Property:Membrane> or <Property:Membrane=1>) and <Feature:Transmembrane>1>
Subcellular location Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2> and <Feature:Transmembrane==1>
Subcellular location Cell inner membrane; Single-pass membrane protein.
else case <Property:Membrane=2> and <Feature:Transmembrane>1>
Subcellular location Cell inner membrane; Multi-pass membrane protein.
end case
Similarity Belongs to the SecE/SEC61-gamma family.

Keywords [?]

case <OC:Cyanobacteria> and not <OC:Gloeobacter>
Cell membrane
Cell inner membrane
Thylakoid
else case <OC:Gloeobacter>
Cell membrane
Cell inner membrane
else case not defined <Property:Membrane> or <Property:Membrane=1>
Cell membrane
else case <Property:Membrane=2>
Cell membrane
Cell inner membrane
end case
Membrane
Protein transport
Translocation
Transmembrane
Transmembrane helix
Transport

Gene Ontology [?]

GO:0008320; Molecular function: protein transmembrane transporter activity.
GO:0009306; Biological process: protein secretion.
GO:0065002; Biological process: intracellular protein transmembrane transport.
GO:0006605; Biological process: protein targeting.
case <OC:Bacteria>
GO:0043952; Biological process: protein transport by the Sec complex.
end case
case <OC:Cyanobacteria> and not <OC:Gloeobacter>
GO:0042651; Cellular component: thylakoid membrane.
end case
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

PROSITE PS01067; SECE_SEC61G; 1;
Pfam PF00584; SecE; 1;
PRINTS PR01650; SECETRNLCASE; 1;
TIGRFAMs TIGR00964; secE_bact; 1;
TIGR00327; secE_euk_arch; 1;

Computed features [?]

General Transmembrane; -; 1-3; trigger=yes;

Additional information [?]

Size range 57-162 amino acids
Related rules None
Fusion None


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