HAMAP rule MF_00429
General rule information
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Accession | MF_00429 |
Dates | 19-JUL-2001 (Created) 11-JAN-2021 (Last updated, Version 40) |
Name | NqrE |
Scope | Bacteria |
Templates | Q56589 (NQRE_VIBAL); A5F5Y5 (NQRE_VIBC3): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. |
Catalytic activity | RHEA:47748: a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)
EC 7.2.1.1 |
Subunit | Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF. |
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location | Cell membrane; Multi-pass membrane protein. |
else case <Property:Membrane=2>
Subcellular location | Cell inner membrane; Multi-pass membrane protein. |
end case
Similarity | Belongs to the NqrDE/RnfAE family. |
Keywords
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Translocase
NAD
Ubiquinone
Transport
Ion transport
Sodium
Sodium transport
Cell membrane
Membrane
Transmembrane
NAD
Ubiquinone
Transport
Ion transport
Sodium
Sodium transport
Cell membrane
Membrane
Transmembrane
case defined <Property:Membrane> and <Property:Membrane=2>
end case
Gene Ontology
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GO:0016655; Molecular function: oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor.
GO:0006814; Biological process: sodium ion transport.
GO:0005886; Cellular component: plasma membrane.
GO:0006814; Biological process: sodium ion transport.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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Pfam | PF02508; Rnf-Nqr; 1; |
PIRSF | PIRSF006102; NQR_DE; 1; |
TIGRFAMs | TIGR01940; NqrE; 1; |
Computed features
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General | Transmembrane; -; 6; trigger=yes; |
Additional information
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Size range | 197-264 amino acids |
Related rules | MF_00428 (NQRD) |
Fusion | None |