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HAMAP rule MF_00429

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General rule information [?]

Accession MF_00429
Dates 19-JUL-2001 (Created)
11-JAN-2021 (Last updated, Version 40)
Name NqrE
Scope
Bacteria
Templates Q56589 (NQRE_VIBAL); A5F5Y5 (NQRE_VIBC3): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
NQRE
Protein name
RecName: Full=Na(+)-translocating NADH-quinone reductase subunit E;
Short=Na(+)-NQR subunit E;
Short=Na(+)-translocating NQR subunit E;
EC 7.2.1.1;
AltName: Full=NQR complex subunit E;
AltName: Full=NQR-1 subunit E;
Gene name
nqrE

Comments [?]

Function NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
Catalytic activity RHEA:47748: a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)
EC 7.2.1.1
Subunit Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
Subcellular location Cell inner membrane; Multi-pass membrane protein.
end case
Similarity Belongs to the NqrDE/RnfAE family.

Keywords [?]

Translocase
NAD
Ubiquinone
Transport
Ion transport
Sodium
Sodium transport
Cell membrane
Membrane
Transmembrane
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Transmembrane helix

Gene Ontology [?]

GO:0016655; Molecular function: oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor.
GO:0006814; Biological process: sodium ion transport.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF02508; Rnf-Nqr; 1;
PIRSF PIRSF006102; NQR_DE; 1;
TIGRFAMs TIGR01940; NqrE; 1;

Computed features [?]

General Transmembrane; -; 6; trigger=yes;

Additional information [?]

Size range 197-264 amino acids
Related rules MF_00428 (NQRD)
Fusion None


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