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HAMAP rule MF_00461

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General rule information [?]

Accession MF_00461
Dates 16-OCT-2001 (Created)
1-JUN-2023 (Last updated, Version 44)
Name RsxC_RnfC
Scope
Archaea
Bacteria
Templates P77611 (RSXC_ECOLI); Q52716 (RNFC_RHOCA); D5ARZ1 (RNFC_RHOCB); H6LC32 (RNFC_ACEWD); D8GR66 (RNFC_CLOLD); A0A0H3AJC2 (RNFC_VIBC3); Q8TSY4 (RNFC_METAC): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
Identifier
RSXC
Protein name
RecName: Full=Ion-translocating oxidoreductase complex subunit C;
EC 7.-.-.-;
AltName: Full=Rsx electron transport complex subunit C;
Gene name
rsxC
else
Identifier
RNFC
Protein name
RecName: Full=Ion-translocating oxidoreductase complex subunit C;
EC 7.-.-.-;
AltName: Full=Rnf electron transport complex subunit C;
Gene name
rnfC
end case

Comments [?]

case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
Function Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR.
else
Function Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
end case
Cofactor [4Fe-4S] cluster
Note: Binds 2 [4Fe-4S] clusters per subunit.
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
Subunit The complex is composed of six subunits: RsxA, RsxB, RsxC, RsxD, RsxE and RsxG.
else case <OC:Bacteria>
Subunit The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.
else case <OC:Archaea>
Subunit The Rnf complex is probably composed of eight subunits, including RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.
end case
case (<OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)) and not <OC:Paracoccaceae>
Subcellular location Cell inner membrane; Peripheral membrane protein.
else case <OC:Paracoccaceae>
Subcellular location Cellular chromatophore membrane; Peripheral membrane protein.
else
Subcellular location Cell membrane; Peripheral membrane protein.
end case
Similarity Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.

Keywords [?]

4Fe-4S
case (<OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)) and not <OC:Paracoccaceae>
Cell inner membrane
end case
case not <OC:Paracoccaceae>
Cell membrane
end case
Electron transport
Iron
Iron-sulfur
Membrane
Metal-binding
case <OC:Paracoccaceae>
Nitrogen fixation
end case
Repeat
Translocase
Transport

Gene Ontology [?]

GO:0022900; Biological process: electron transport chain.
case <OC:Paracoccaceae>
GO:0009399; Biological process: nitrogen fixation.
end case
case not <OC:Paracoccaceae>
GO:0005886; Cellular component: plasma membrane.
end case

Cross-references [?]

Pfam PF01512; Complex1_51K; 1;
PF00037; Fer4; 2;
PRINTS PR00353; 4FE4SFRDOXIN; 1;
NCBIfam TIGR01945; rnfC; 1;
PROSITE PS00198; 4FE4S_FER_1; 2;
PS51379; 4FE4S_FER_2; 2; trigger=PRU00711;

Features [?]

From: RNFC_RHOCA (Q52716)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     381     381       /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="1     C  
BINDING     384     384       /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="1     C  
BINDING     387     387       /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="1     C  
BINDING     391     391       /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2     C  
BINDING     420     420       /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2     C  
BINDING     423     423       /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2     C  
BINDING     426     426       /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2     C  
BINDING     430     430       /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="1     C  

Additional information [?]

Size range 400-1000 amino acids
Related rules None
Fusion None
Comments Highly divergent C-terminal sequences.


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