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Annotation rule MF_00463
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General rule information [?]

Accession MF_00463
Dates 15-OCT-2001 (Created)
18-NOV-2019 (Last updated, Version 46)
Name RsxB_RnfB
Scope
Archaea
Bacteria
Templates P77223 (RSXB_ECOLI); P0CZ14 (RNFB_RHOCA); D5ARZ0 (RNFB_RHOCB); A5F2R3 (RNFB_VIBC3); H6LC27 (RNFB_ACEWD); D8GR71 (RNFB_CLOLD); Q8TSX9 (RNFB_METAC): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
Identifier
RSXB
Protein name
RecName: Full=Ion-translocating oxidoreductase complex subunit B;
EC 7.-.-.-;
AltName: Full=Rsx electron transport complex subunit B;
Gene name
rsxB
else
Identifier
RNFB
Protein name
RecName: Full=Ion-translocating oxidoreductase complex subunit B;
EC 7.-.-.-;
AltName: Full=Rnf electron transport complex subunit B;
Gene name
rnfB
end case

Comments [?]

case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
Function Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR.
else
Function Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
end case
case <FTGroup:1> and (<FTGroup:2> or <FTGroup:4>) and <FTGroup:3> and not <FTGroup:5>
Cofactor [4Fe-4S] cluster
Note: Binds 3 [4Fe-4S] clusters
else case <FTGroup:1> and (<FTGroup:2> or <FTGroup:4>) and <FTGroup:3> and <FTGroup:5>
Cofactor [4Fe-4S] cluster
Note: Binds 4 [4Fe-4S] clusters
else
Cofactor [4Fe-4S] cluster
end case
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
Subunit The complex is composed of six subunits: RsxA, RsxB, RsxC, RsxD, RsxE and RsxG.
else case <OC:Bacteria>
Subunit The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.
else case <OC:Archaea>
Subunit The Rnf complex is probably composed of eight subunits, including RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.
end case
case (<OC:Proteobacteria> or (defined <Property:Membrane> and <Property:Membrane=2>)) and not <OC:Rhodobacteraceae>
Subcellular location Cell inner membrane.
else case <OC:Rhodobacteraceae>
Subcellular location Cellular chromatophore membrane; Peripheral membrane protein; Cytoplasmic side.
else
Subcellular location Cell membrane.
end case
Similarity Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.

Keywords [?]

case (<OC:Proteobacteria> or (defined <Property:Membrane> and <Property:Membrane=2>)) and not <OC:Rhodobacteraceae>
end case
case not <OC:Rhodobacteraceae>
end case
case <OC:Rhodobacteraceae>
end case

Gene Ontology [?]

GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding.
GO:0022900; Biological process: electron transport chain.
GO:0055114; Biological process: oxidation-reduction process.
case <OC:Rhodobacteraceae>
GO:0009399; Biological process: nitrogen fixation.
end case
case not <OC:Rhodobacteraceae>
GO:0005886; Cellular component: plasma membrane.
end case

Cross-references [?]

Pfam PF00037; Fer4; 2;
PF04060; FeS; 1;
PRINTS PR00353; 4FE4SFRDOXIN; 1;
TIGRFAMs TIGR01944; rnfB; 1;
PROSITE PS51656; 4FE4S; 1; trigger=PRU00989;
PS00198; 4FE4S_FER_1; 2;
PS51379; 4FE4S_FER_2; 2; trigger=PRU00711;

Features [?]

From: RNFB_RHOCA (P0CZ14)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     Nter     23       Hydrophobic        
METAL     46     46       Iron-sulfur 1 (4Fe-4S)     C   1
METAL     49     49       Iron-sulfur 1 (4Fe-4S)     C   1
METAL     54     54       Iron-sulfur 1 (4Fe-4S)     C   1
METAL     71     71       Iron-sulfur 1 (4Fe-4S)     C   1
METAL (Optional)     112     112       Iron-sulfur 2 (4Fe-4S)     C   2
METAL (Optional)     115     115       Iron-sulfur 2 (4Fe-4S)     C   2
METAL (Optional)     118     118       Iron-sulfur 2 (4Fe-4S)     C   2
METAL     122     122       Iron-sulfur 3 (4Fe-4S)     C   3
METAL     142     142       Iron-sulfur 3 (4Fe-4S)     C   3
METAL     145     145       Iron-sulfur 3 (4Fe-4S)     C   3
METAL     148     148       Iron-sulfur 3 (4Fe-4S)     C   3
METAL (Optional)     152     152       Iron-sulfur 2 (4Fe-4S)     C   2
From: RNFB_ACEWD (H6LC27)
METAL (Optional)     138     138       Iron-sulfur 2 (4Fe-4S)     C   4
METAL (Optional)     142     142       Iron-sulfur 2 (4Fe-4S)     C   4
METAL (Optional)     148     148       Iron-sulfur 2 (4Fe-4S)     C   4
METAL (Optional)     182     182       Iron-sulfur 2 (4Fe-4S)     C   4
METAL (Optional)     217     217       Iron-sulfur 4 (4Fe-4S)     C   5
METAL (Optional)     220     220       Iron-sulfur 4 (4Fe-4S)     C   5
METAL (Optional)     223     223       Iron-sulfur 4 (4Fe-4S)     C   5
METAL (Optional)     227     227       Iron-sulfur 4 (4Fe-4S)     C   5

Additional information [?]

Size range 160-400 amino acids
Related rules None
Fusion None
Comments According to PubMed:9154934, this protein is a peripheral membrane protein, and the N-terminal hydrophobic stretch is not a membrane anchor. According to PubMed:25831459, this protein is a transmembrane protein.