HAMAP rule MF_00463
General rule information
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Accession | MF_00463 |
Dates | 15-OCT-2001 (Created)
1-JUN-2023 (Last updated, Version 52) |
Name | RsxB_RnfB |
Scope(s) |
Archaea Bacteria |
Template(s) | P77223 (RSXB_ECOLI); P0CZ14 (RNFB_RHOCA); D5ARZ0 (RNFB_RHOCB); A5F2R3 (RNFB_VIBC3); H6LC27 (RNFB_ACEWD); D8GR71 (RNFB_CLOLD); Q8TSX9 (RNFB_METAC); [ Recover all ] |
Triggered by |
HAMAP; MF_00463 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella> | |
Identifier | RSXB |
Protein name | RecName: Full=Ion-translocating oxidoreductase complex subunit B; EC=7.-.-.-; AltName: Full=Rsx electron transport complex subunit B; |
Gene name | Name=rsxB; |
else | |
Identifier | RNFB |
Protein name | RecName: Full=Ion-translocating oxidoreductase complex subunit B; EC=7.-.-.-; AltName: Full=Rnf electron transport complex subunit B; |
Gene name | Name=rnfB; |
end case |
Comments
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case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella> | |
FUNCTION | Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. |
else | |
FUNCTION | Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. |
end case | |
case <FTGroup:1> and (<FTGroup:2> or <FTGroup:4>) and <FTGroup:3> and not <FTGroup:5> | |
COFACTOR | Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Note=Binds 3 [4Fe-4S] clusters |
else case <FTGroup:1> and (<FTGroup:2> or <FTGroup:4>) and <FTGroup:3> and <FTGroup:5> | |
COFACTOR | Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Note=Binds 4 [4Fe-4S] clusters |
else | |
COFACTOR | Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; |
end case | |
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella> | |
SUBUNIT | The complex is composed of six subunits: RsxA, RsxB, RsxC, RsxD, RsxE and RsxG. |
else case <OC:Bacteria> | |
SUBUNIT | The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. |
else case <OC:Archaea> | |
SUBUNIT | The Rnf complex is probably composed of eight subunits, including RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. |
end case | |
case (<OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)) and not <OC:Paracoccaceae> | |
SUBCELLULAR LOCATION | Cell inner membrane. |
else case <OC:Paracoccaceae> | |
SUBCELLULAR LOCATION | Cellular chromatophore membrane; Peripheral membrane protein; Cytoplasmic side. |
else | |
SUBCELLULAR LOCATION | Cell membrane. |
end case | |
SIMILARITY | Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. |
Keywords
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4Fe-4S | |
case (<OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)) and not <OC:Paracoccaceae> | |
Cell inner membrane | |
end case | |
case not <OC:Paracoccaceae> | |
Cell membrane | |
end case | |
Electron transport | |
Iron | |
Iron-sulfur | |
Membrane | |
Metal-binding | |
case <OC:Paracoccaceae> | |
Nitrogen fixation | |
end case | |
Repeat | |
<a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a> | |
Transport |
Gene Ontology
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GO:0051539; Molecular function:4 iron, 4 sulfur cluster binding | |
GO:0022900; Biological process:electron transport chain | |
case <OCellular component:Paracoccaceae> | |
GO:0009399; Biological process:nitrogen fixation | |
end case | |
case not <OCellular component:Paracoccaceae> | |
GO:0005886; Cellular component:plasma membrane | |
end case |
Cross-references
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Pfam | PF00037; Fer4; 2; |
Pfam | PF04060; FeS; 1; |
PRINTS | PR00353; 4FE4SFRDOXIN; 1; |
NCBIfam | TIGR01944; rnfB; 1; |
PROSITE | PS51656; 4FE4S; 1; |
PROSITE | PS00198; 4FE4S_FER_1; 2; |
PROSITE | PS51379; 4FE4S_FER_2; 2; |
Features
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From: RNFB_RHOCA (P0CZ14) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
REGION | Nter | 23 | /note="Hydrophobic" | |||||||||
BINDING | 46 | 46 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="1" |
C | 1 | |||||||
BINDING | 49 | 49 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="1" |
C | 1 | |||||||
BINDING | 54 | 54 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="1" |
C | 1 | |||||||
BINDING | 71 | 71 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="1" |
C | 1 | |||||||
BINDING | 112 | 112 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2" |
C | 2 | |||||||
BINDING | 115 | 115 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2" |
C | 2 | |||||||
BINDING | 118 | 118 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2" |
C | 2 | |||||||
BINDING | 122 | 122 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="3" |
C | 3 | |||||||
BINDING | 142 | 142 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="3" |
C | 3 | |||||||
BINDING | 145 | 145 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="3" |
C | 3 | |||||||
BINDING | 148 | 148 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="3" |
C | 3 | |||||||
BINDING | 152 | 152 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2" |
C | 2 | |||||||
From: RNFB_ACEWD (H6LC27) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 138 | 138 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2" |
C | 4 | |||||||
BINDING | 142 | 142 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2" |
C | 4 | |||||||
BINDING | 148 | 148 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2" |
C | 4 | |||||||
BINDING | 182 | 182 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="2" |
C | 4 | |||||||
BINDING | 217 | 217 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="4" |
C | 5 | |||||||
BINDING | 220 | 220 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="4" |
C | 5 | |||||||
BINDING | 223 | 223 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="4" |
C | 5 | |||||||
BINDING | 227 | 227 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="4" |
C | 5 |
Additional information
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Size range | 160-400 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |
Comments | According to PubMed:9154934, this protein is a peripheral membrane protein, and the N-terminal hydrophobic stretch is not a membrane anchor. According to PubMed:25831459, this protein is a transmembrane protein. |