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Annotation rule MF_00475
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General rule information [?]

Accession MF_00475
Dates 25-OCT-2001 (Created)
18-NOV-2019 (Last updated, Version 28)
Name Trp_repressor
Scope
Bacteria
Template P0A881 (TRPR_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
TRPR
case <OC:Enterobacterales>
Protein name
RecName: Full=Trp operon repressor;
else
Protein name
RecName: Full=Trp operon repressor homolog;
end case
Gene name
trpR

Comments [?]

case <OC:Enterobacterales>
Function This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
else
Function This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription.
end case
Subunit Homodimer.
Subcellular location Cytoplasm.
Similarity Belongs to the TrpR family.

Keywords [?]

Cytoplasm
Transcription
Transcription regulation
Repressor
DNA-binding

Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
GO:0045892; Biological process: negative regulation of transcription, DNA-templated.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01371; Trp_repressor; 1;
TIGRFAMs TIGR01321; TrpR; 1;

Features [?]

From: TRPR_ECOLI (P0A881)
Key     From     To       Description   Tag   Condition   FTGroup
DNA_BIND     68     91                

Additional information [?]

Size range 92-125 amino acids
Related rules None
Fusion None


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