HAMAP rule MF_00475
General rule information
[?]
Accession | MF_00475 |
Dates | 25-OCT-2001 (Created)
1-JUN-2023 (Last updated, Version 30) |
Name | Trp_repressor |
Scope(s) |
Bacteria |
Template(s) | P0A881 (TRPR_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_00475 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier | TRPR |
case <OC:Enterobacterales> | |
Protein name | RecName: Full=Trp operon repressor; |
else | |
Protein name | RecName: Full=Trp operon repressor homolog; |
end case | |
Gene name | Name=trpR; |
Comments
[?]
case <OC:Enterobacterales> | |
FUNCTION | This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. |
else | |
FUNCTION | This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription. |
end case | |
SUBUNIT | Homodimer. |
SUBCELLULAR LOCATION | Cytoplasm. |
SIMILARITY | Belongs to the TrpR family. |
Keywords
[?]
Gene Ontology
[?]
GO:0003677; Molecular function:DNA binding |
GO:0045892; Biological process:negative regulation of DNA-templated transcription |
GO:0005737; Cellular component:cytoplasm |
Cross-references
[?]
Features
[?]
From: TRPR_ECOLI (P0A881) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DNA_BIND | 68 | 91 |
Additional information
[?]
Size range | 92-125 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |