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Annotation rule MF_00475 |
General rule information
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Accession |
MF_00475 |
Dates |
25-OCT-2001 (Created) 18-NOV-2019 (Last updated, Version 28) |
Propagated annotation
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Identifier, protein and gene names
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case <OC:Enterobacterales>
Protein name |
RecName:
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Full=Trp operon repressor;
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else
Protein name |
RecName:
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Full=Trp operon repressor homolog;
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end case
case <OC:Enterobacterales>
Function |
This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. |
else
Function |
This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription. |
end case
Subunit |
Homodimer. |
Subcellular location |
Cytoplasm. |
Similarity |
Belongs to the TrpR family. |
GO:0003677; Molecular function: DNA binding.
GO:0045892; Biological process: negative regulation of transcription, DNA-templated.
GO:0005737; Cellular component: cytoplasm.
From: TRPR_ECOLI (P0A881) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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DNA_BIND
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68
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91
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Additional information
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Size range |
92-125 amino acids |
Related rules |
None |
Fusion |
None |