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Annotation rule MF_00492
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General rule information [?]

Accession MF_00492
Dates 28-NOV-2001 (Created)
18-NOV-2019 (Last updated, Version 33)
Name Transaldolase_1
Scope
Bacteria
Templates P0A867 (TALA_ECOLI); P0A870 (TALB_ECOLI): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
TAL
Protein name
RecName: Full=Transaldolase;
EC 2.2.1.2;
Gene name
tal

Comments [?]

Function Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Catalytic activity RHEA:17053: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate
EC 2.2.1.2
Pathway Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.
Subcellular location Cytoplasm.
Similarity Belongs to the transaldolase family. Type 1 subfamily.

Keywords [?]


Gene Ontology [?]

GO:0004801; Molecular function: sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity.
GO:0006098; Biological process: pentose-phosphate shunt.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00923; Transaldolase; 1;
PROSITE PS01054; TRANSALDOLASE_1; 1;
PS00958; TRANSALDOLASE_2; 1;
TIGRFAMs TIGR00874; talAB; 1;

Features [?]

From: TALB_ECOLI (P0A870)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     132     132       Schiff-base intermediate with substrate     K  

Additional information [?]

Size range 307-397 amino acids
Related rules MF_00493 (TAL); MF_00494 (TAL); MF_00496 (FSA)
Fusion Nter: None; Cter: <Unknown>
Comments C-terminal domain that contains 2 EF-hands in GLOVI, PROMM, THEEB, SYNPX, SYNY3