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HAMAP rule MF_00492

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General rule information [?]

Accession MF_00492
Dates 28-NOV-2001 (Created)
1-JUN-2023 (Last updated, Version 37)
Name Transaldolase_1
Scope(s) Bacteria
Template(s) P0A867 (TALA_ECOLI); P0A870 (TALB_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00492 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier TAL
Protein name RecName: Full=Transaldolase;
                 EC=2.2.1.2;
Gene name Name=tal;

Comments [?]

FUNCTIONTransaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
CATALYTIC ACTIVITY Reaction=D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate; Xref=Rhea:RHEA:17053, ChEBI:CHEBI:16897, ChEBI:CHEBI:57483, ChEBI:CHEBI:57634, ChEBI:CHEBI:59776; EC=2.2.1.2;
PATHWAYCarbohydrate degradation; pentose phosphate pathway; D- glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D- ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the transaldolase family. Type 1 subfamily.

Keywords [?]


Gene Ontology [?]

GO:0004801; Molecular function:transaldolase activity
GO:0006098; Biological process:pentose-phosphate shunt
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF00923; Transaldolase; 1;
PROSITE PS01054; TRANSALDOLASE_1; 1;
PROSITE PS00958; TRANSALDOLASE_2; 1;
NCBIfam TIGR00874; talAB; 1;

Features [?]

From: TALB_ECOLI (P0A870)
Key From To Description Tag Condition FTGroup
ACT_SITE 132 132 /note="Schiff-base intermediate with substrate" K

Additional information [?]

Size range 307-397 amino acids
Related rules MF_00493
MF_00494
MF_00496
Fusion Nter: None Cter: <Unknown>
Comments C-terminal domain that contains 2 EF-hands in GLOVI, PROMM, THEVB, PARMW, SYNY3



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