HAMAP rule MF_00496
General rule information
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| Accession | MF_00496 |
| Dates | 30-NOV-2001 (Created)
1-JUN-2023 (Last updated, Version 25) |
| Name | F6P_aldolase |
| Scope(s) |
Bacteria |
| Template(s) | P78055 (FSAA_ECOLI); P32669 (FSAB_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00496 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | FSA |
| case <OC:Enterobacterales> | |
| Protein name | RecName: Full=Fructose-6-phosphate aldolase; EC=4.1.2.-; |
| else | |
| Protein name | RecName: Full=Probable fructose-6-phosphate aldolase; EC=4.1.2.-; |
| end case | |
| Gene name | Name=fsa; |
Comments
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| FUNCTION | Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction. |
| CATALYTIC ACTIVITY | Reaction=beta-D-fructose 6-phosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone; Xref=Rhea:RHEA:28002, ChEBI:CHEBI:16016, ChEBI:CHEBI:57634, ChEBI:CHEBI:59776; |
| case <OC:Enterobacterales> | |
| SUBUNIT | Homodecamer. |
| end case | |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the transaldolase family. Type 3A subfamily. |
Keywords
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Gene Ontology
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| GO:0016832; Molecular function:aldehyde-lyase activity |
| GO:0006000; Biological process:fructose metabolic process |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF00923; Transaldolase; 1; |
| NCBIfam | TIGR00875; fsa_talC_mipB; 1; |
| PROSITE | PS01054; TRANSALDOLASE_1; 1; |
| PROSITE | PS00958; TRANSALDOLASE_2; 1; |
Features
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| From: FSAA_ECOLI (P78055) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 85 | 85 | /note="Schiff-base intermediate with substrate" | K | ||||||||
Additional information
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| Size range | 220-222 amino acids |
| Related rules |
MF_00492 MF_00493 MF_00494 |
| Fusion | Nter: None Cter: None |