HAMAP rule MF_00496

General rule information [?]

Accession	MF_00496
Dates	30-NOV-2001 (Created) 1-JUN-2023 (Last updated, Version 25)

Name	F6P_aldolase

Scope

Bacteria

Templates

P78055 (FSAA_ECOLI); P32669 (FSAB_ECOLI): [Recover all]

Triggered by

HAMAP; MF_00496 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

FSA

case <OC:Enterobacterales>

Protein name

RecName:		Full=Fructose-6-phosphate aldolase;
		EC 4.1.2.-;

else

Protein name

RecName:		Full=Probable fructose-6-phosphate aldolase;
		EC 4.1.2.-;

end case

Gene name

fsa

Comments [?]

Function	Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction.
Catalytic activity	RHEA:28002: beta-D-fructose 6-phosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone

case <OC:Enterobacterales>

Subunit

Homodecamer.

end case

Subcellular location	Cytoplasm.
Similarity	Belongs to the transaldolase family. Type 3A subfamily.

Keywords [?]

Carbohydrate metabolism
Cytoplasm
Lyase
Schiff base

Gene Ontology [?]

GO:0016832; Molecular function: aldehyde-lyase activity.
GO:0006000; Biological process: fructose metabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF00923; Transaldolase; 1;
NCBIfam	TIGR00875; fsa_talC_mipB; 1;
PROSITE	PS01054; TRANSALDOLASE_1; 1;
	PS00958; TRANSALDOLASE_2; 1;

Features [?]

From: FSAA_ECOLI (P78055)

Key From To Description Tag Condition FTGroup

ACT_SITE 85 85 Schiff-base intermediate with substrate K

Additional information [?]

Size range	220-222 amino acids
Related rules	MF_00492 (TAL); MF_00493 (TAL); MF_00494 (TAL)
Fusion	None

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