HAMAP rule MF_00521
General rule information
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Accession | MF_00521 |
Dates | 8-JAN-2002 (Created) 25-SEP-2022 (Last updated, Version 29) |
Name | KDO_kinase |
Scope | Bacteria |
Template | O86224 (KDKA_HAEIN) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position. |
case <OC:Escherichia>
Catalytic activity | RHEA:28506: alpha-Kdo-(2->6)-lipid IVA (E. coli) + ATP = 4-O-phospho-alpha-Kdo-(2->6)-lipid IVA (E. coli) + ADP + H(+)
EC 2.7.1.166 |
else
Catalytic activity | RHEA:74271: an alpha-Kdo-(2->6)-lipid IVA + ATP = a 4-O-phospho-alpha-Kdo-(2->6)-lipid IVA + ADP + H(+)
EC 2.7.1.166 |
end case
Pathway | Bacterial outer membrane biogenesis; LPS core biosynthesis. |
Subcellular location | Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. |
Similarity | Belongs to the protein kinase superfamily. KdkA/RfaP family. |
Keywords
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ATP-binding
Cell inner membrane
Cell membrane
Kinase
Lipopolysaccharide biosynthesis
Membrane
Nucleotide-binding
Transferase
Cell inner membrane
Cell membrane
Kinase
Lipopolysaccharide biosynthesis
Membrane
Nucleotide-binding
Transferase
Gene Ontology
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GO:0005524; Molecular function: ATP binding.
GO:0016773; Molecular function: phosphotransferase activity, alcohol group as acceptor.
GO:0009103; Biological process: lipopolysaccharide biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
GO:0016773; Molecular function: phosphotransferase activity, alcohol group as acceptor.
GO:0009103; Biological process: lipopolysaccharide biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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Pfam | PF06293; Kdo; 1; |
Features
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From: KDKA_HAEIN (O86224) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 171 | 171 | D |
Additional information
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Size range | 235-259 amino acids |
Related rules | None |
Fusion | None |