HAMAP rule MF_00543
General rule information
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| Accession | MF_00543 |
| Dates | 8-MAR-2002 (Created)
3-SEP-2024 (Last updated, Version 25) |
| Name | Tyr_phenol_lyase |
| Scope(s) |
Bacteria |
| Template(s) | P31013 (TPL_CITFR); [ Recover all ] |
| Triggered by |
HAMAP; MF_00543 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | TPL |
| Protein name | RecName: Full=Tyrosine phenol-lyase; EC=4.1.99.2; AltName: Full=Beta-tyrosinase; |
| Gene name | Name=tpl; |
Comments
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| CATALYTIC ACTIVITY | Reaction=L-tyrosine + H2O = phenol + pyruvate + NH4(+); Xref=Rhea:RHEA:21704, ChEBI:CHEBI:15361, ChEBI:CHEBI:15377, ChEBI:CHEBI:15882, ChEBI:CHEBI:28938, ChEBI:CHEBI:58315; EC=4.1.99.2; |
| COFACTOR | Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; |
| SUBUNIT | Homotetramer. |
| SIMILARITY | Belongs to the beta-eliminating lyase family. |
Keywords
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Gene Ontology
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| GO:0050371; Molecular function:tyrosine phenol-lyase activity |
Cross-references
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| Pfam | PF01212; Beta_elim_lyase; 1; |
| PIRSF | PIRSF001386; Trpase; 1; |
| NCBIfam | TIGR02618; Tyr_phenol_ly; 1; |
| PROSITE | PS00853; BETA_ELIM_LYASE; 1; |
Features
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| From: TPL_CITFR (P31013) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| MOD_RES | 257 | 257 | /note="N6-(pyridoxal phosphate)lysine" | K | ||||||||
Additional information
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| Size range | 456-473 amino acids |
| Related rules |
MF_00544 |
| Fusion | Nter: None Cter: None |