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Annotation rule MF_00549 |
Accession | MF_00549 |
Dates | 25-MAR-2002 (Created) 18-NOV-2019 (Last updated, Version 19) |
Name | Methylglyoxal_synth |
Scope | Archaea
Bacteria |
Template | P0A731 (MGSA_ECOLI) |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. |
Catalytic activity | RHEA:17937: dihydroxyacetone phosphate = methylglyoxal + phosphate
EC 4.2.3.3 |
Similarity | Belongs to the methylglyoxal synthase family. |
Pfam | PF02142; MGS; 1; |
TIGRFAMs | TIGR00160; MGSA; 1; |
PIRSF | PIRSF006614; Methylglyox_syn; 1; |
PROSITE | PS01335; METHYLGLYOXAL_SYNTH; 1; |
PS51855; MGS; 1; trigger=PRU01202; |
From: MGSA_ECOLI (P0A731) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
REGION (Optional) | 45 | 48 | Substrate binding | T-G-[TAS]-T | ||||||||
REGION (Optional) | 65 | 66 | Substrate binding | S-G | ||||||||
ACT_SITE | 71 | 71 | Proton donor/acceptor | D | ||||||||
BINDING | 19 | 19 | Substrate | H | ||||||||
BINDING | 23 | 23 | Substrate | K | ||||||||
BINDING | 98 | 98 | Substrate | H |
Size range | 110-210 amino acids |
Related rules | None |
Fusion | None |
Comments | Divergent SYNY3 with an unknown C-terminal domain not shown in alignment and not used in size range |