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Annotation rule MF_00551
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General rule information [?]

Accession MF_00551
Dates 29-APR-2002 (Created)
18-NOV-2019 (Last updated, Version 22)
Name Uridine_kinase
Scope
Bacteria
Archaea
Template P0A8F4 (URK_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
URK
Protein name
RecName: Full=Uridine kinase;
EC 2.7.1.48;
AltName: Full=Cytidine monophosphokinase;
AltName: Full=Uridine monophosphokinase;
Gene name
udk

Comments [?]

Catalytic activity RHEA:16825: ATP + uridine = ADP + H(+) + UMP
EC 2.7.1.48
RHEA:24674: ATP + cytidine = ADP + CMP + H(+)
Pathway Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.
Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.
Subcellular location Cytoplasm.
Similarity Belongs to the uridine kinase family.

Keywords [?]

Cytoplasm
Transferase
Kinase
ATP-binding
Nucleotide-binding

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0004849; Molecular function: uridine kinase activity.
GO:0008655; Biological process: pyrimidine-containing compound salvage.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00485; PRK; 1;
PRINTS PR00478; PHRIBLKINASE; 1;
PR00988; URIDINKINASE; 1;
TIGRFAMs TIGR00235; Udk; 1;

Features [?]

From: URK_ECOLI (P0A8F4)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     15     22       ATP     G-[GA]-[ST]-[GAC]-[GSA]-G-K-[ST]  

Additional information [?]

Size range 205-225 amino acids
Related rules None
Fusion None


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