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Annotation rule MF_00557
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General rule information [?]

Accession MF_00557
Dates 23-MAY-2002 (Created)
18-NOV-2019 (Last updated, Version 23)
Name Alginate_lyase
Scope
Bacteria
Templates Q06749 (ALGL_PSEAE); O50660 (ALGL_AZOCH); O52195 (ALGL_AZOVI); Q9L7P2 (ALGL_PSESY): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ALGL
Protein name
RecName: Full=Alginate lyase;
EC 4.2.2.3;
AltName: Full=Poly(beta-D-mannuronate) lyase;
Flags: Precursor;
Gene name
algL

Comments [?]

case defined <Property:Membrane> and <Property:Membrane=2>
Function Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. May serve to degrade mislocalized alginate that is trapped in the periplasmic space.
else
Function Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism.
end case
Catalytic activity Reaction=Eliminative cleavage of alginate to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl groups at their non-reducing ends and beta-D-mannuronate at their reducing end.; EC=4.2.2.3;
case defined <Property:Membrane> and <Property:Membrane=2>
Subcellular location Periplasm.
end case
Similarity Belongs to the polysaccharide lyase 5 family.

Keywords [?]

Lyase
Signal
case defined <Property:Membrane> and <Property:Membrane=2>
Periplasm
end case

Gene Ontology [?]

GO:0045135; Molecular function: poly(beta-D-mannuronate) lyase activity.
GO:0042122; Biological process: alginic acid catabolic process.
case defined <Property:Membrane> and <Property:Membrane=2>
GO:0042597; Cellular component: periplasmic space.
end case

Cross-references [?]

Pfam PF05426; Alginate_lyase; 1;

Computed features [?]

General Signal; -; 1; trigger=yes;

Features [?]

From: ALGL_PSEAE (Q06749)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     65     66       Substrate binding     S-K  
REGION     138     139       Substrate binding     H-T  
BINDING     256     256       Substrate     Y  

Additional information [?]

Size range 367-378 amino acids
Related rules None
Fusion None


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