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HAMAP rule MF_00557

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General rule information [?]

Accession MF_00557
Dates 23-MAY-2002 (Created)
14-MAY-2022 (Last updated, Version 26)
Name Alginate_lyase
Scope(s) Bacteria
Template(s) Q06749 (ALGL_PSEAE); O50660 (ALGL_AZOCH); O52195 (ALGL_AZOVI); Q9L7P2 (ALGL_PSESY); [ Recover all ]
Triggered by HAMAP; MF_00557 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ALGL
Protein name RecName: Full=Alginate lyase;
                 EC=4.2.2.3;
AltName: Full=Poly(beta-D-mannuronate) lyase;
case <Feature:Signal>
Protein name + Flags: Precursor;
end case
Gene name Name=algL;

Comments [?]

case defined <Property:Membrane> and <Property:Membrane=2>
FUNCTIONCatalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. May serve to degrade mislocalized alginate that is trapped in the periplasmic space.
else
FUNCTIONCatalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism.
end case
CATALYTIC ACTIVITY Reaction=Eliminative cleavage of alginate to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl groups at their non-reducing ends and beta-D-mannuronate at their reducing end.; EC=4.2.2.3;
case defined <Property:Membrane> and <Property:Membrane=2>
SUBCELLULAR LOCATIONPeriplasm.
end case
SIMILARITYBelongs to the polysaccharide lyase 5 family.

Keywords [?]

Lyase
case <Feature:Signal>
Signal
end case
case defined <Property:Membrane> and <Property:Membrane=2>
Periplasm
end case

Gene Ontology [?]

GO:0045135; Molecular function:poly(beta-D-mannuronate) lyase activity
GO:0042122; Biological process:alginic acid catabolic process
case defined <Property:Membrane> and <Property:Membrane=2>
GO:0042597; Cellular component:periplasmic space
end case

Cross-references [?]

Pfam PF05426; Alginate_lyase; 1;
General Signal; -; 1;

Features [?]

From: ALGL_PSEAE (Q06749)
Key From To Description Tag Condition FTGroup
BINDING 65 66 /ligand="substrate" S-K
BINDING 138 139 /ligand="substrate" H-T
BINDING 256 256 /ligand="substrate" Y

Additional information [?]

Size range 367-378 amino acids
Related rules None
Fusion Nter: None Cter: None



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