HAMAP rule MF_00557
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00557 |
| Accession | MF_00557 |
| Dates | 23-MAY-2002 (Created)
14-MAY-2022 (Last updated, Version 26) |
| Name | Alginate_lyase |
| Scope(s) |
Bacteria |
| Template(s) | Q06749 (ALGL_PSEAE); O50660 (ALGL_AZOCH); O52195 (ALGL_AZOVI); Q9L7P2 (ALGL_PSESY); [ Recover all ] |
| Triggered by |
HAMAP; MF_00557 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | ALGL |
| Protein name | RecName: Full=Alginate lyase; EC=4.2.2.3; AltName: Full=Poly(beta-D-mannuronate) lyase; |
| case <Feature:Signal> | |
| Protein name | + Flags: Precursor; |
| end case | |
| Gene name | Name=algL; |
Comments
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| case defined <Property:Membrane> and <Property:Membrane=2> | |
| FUNCTION | Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. May serve to degrade mislocalized alginate that is trapped in the periplasmic space. |
| else | |
| FUNCTION | Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. |
| end case | |
| CATALYTIC ACTIVITY | Reaction=Eliminative cleavage of alginate to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl groups at their non-reducing ends and beta-D-mannuronate at their reducing end.; EC=4.2.2.3; |
| case defined <Property:Membrane> and <Property:Membrane=2> | |
| SUBCELLULAR LOCATION | Periplasm. |
| end case | |
| SIMILARITY | Belongs to the polysaccharide lyase 5 family. |
Keywords
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| Lyase | |
| case <Feature:Signal> | |
| Signal | |
| end case | |
| case defined <Property:Membrane> and <Property:Membrane=2> | |
| Periplasm | |
| end case | |
Gene Ontology
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| GO:0045135; Molecular function:poly(beta-D-mannuronate) lyase activity | |
| GO:0042122; Biological process:alginic acid catabolic process | |
| case defined <Property:Membrane> and <Property:Membrane=2> | |
| GO:0042597; Cellular component:periplasmic space | |
| end case | |
Cross-references
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Features
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| From: ALGL_PSEAE (Q06749) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 65 | 66 | /ligand="substrate" | S-K | ||||||||
| BINDING | 138 | 139 | /ligand="substrate" | H-T | ||||||||
| BINDING | 256 | 256 | /ligand="substrate" | Y | ||||||||
Additional information
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| Size range | 367-378 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |