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Annotation rule MF_00561
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General rule information [?]

Accession MF_00561
Dates 28-MAY-2002 (Created)
18-NOV-2019 (Last updated, Version 26)
Name ADP_PFKinase
Scope
Archaea
Templates Q58999 (K6PF_METJA); Q9V2Z7 (K6PF_PYRFU): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
K6PF
Protein name
RecName: Full=ADP-specific phosphofructokinase;
EC 2.7.1.146;
AltName: Full=ADP-dependent phosphofructokinase;
Short=ADP-Pfk;
Gene name
pfkC

Comments [?]

Function Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
Catalytic activity RHEA:20105: ADP + beta-D-fructose 6-phosphate = AMP + beta-D-fructose 1,6-bisphosphate + H(+)
EC 2.7.1.146
Cofactor Mg(2+)
Note: Binds 1 Mg(2+) ion per subunit.
Pathway Carbohydrate degradation; glycolysis.
Subcellular location Cytoplasm.
Similarity Belongs to the carbohydrate kinase PfkC family.

Keywords [?]


Gene Ontology [?]

GO:0016773; Molecular function: phosphotransferase activity, alcohol group as acceptor.
GO:0006096; Biological process: glycolytic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF04587; ADP_PFK_GK; 1;
PROSITE PS51255; ADPK; 1; trigger=PRU00584;
TIGRFAMs TIGR02045; P_fruct_ADP; 1;

Features [?]

From: K6PF_METJA (Q58999)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     442     442       Proton acceptor     D  
METAL     272     272       Magnesium     E  
METAL     302     302       Magnesium     E  
METAL     442     442       Magnesium     D  

Additional information [?]

Size range 440-505 amino acids
Related rules MF_00809 (GLKA)
Fusion None