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HAMAP rule MF_00561

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General rule information [?]

Accession MF_00561
Dates 28-MAY-2002 (Created)
1-JUN-2023 (Last updated, Version 29)
Name ADP_PFKinase
Scope(s) Archaea
Template(s) Q58999 (K6PF_METJA); Q9V2Z7 (K6PF_PYRFU); [ Recover all ]
Triggered by HAMAP; MF_00561 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier K6PF
Protein name RecName: Full=ADP-specific phosphofructokinase;
AltName: Full=ADP-dependent phosphofructokinase;
Gene name Name=pfkC;

Comments [?]

FUNCTIONCatalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
CATALYTIC ACTIVITY Reaction=ADP + beta-D-fructose 6-phosphate = AMP + beta-D-fructose 1,6- bisphosphate + H(+); Xref=Rhea:RHEA:20105, ChEBI:CHEBI:15378, ChEBI:CHEBI:32966, ChEBI:CHEBI:57634, ChEBI:CHEBI:456215, ChEBI:CHEBI:456216; EC=;
COFACTOR Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Note=Binds 1 Mg(2+) ion per subunit.;
PATHWAYCarbohydrate degradation; glycolysis.
SIMILARITYBelongs to the carbohydrate kinase PfkC family.

Keywords [?]

Gene Ontology [?]

GO:0016773; Molecular function:phosphotransferase activity, alcohol group as acceptor
GO:0006096; Biological process:glycolytic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF04587; ADP_PFK_GK; 1;
NCBIfam TIGR02045; P_fruct_ADP; 1;

Features [?]

From: K6PF_METJA (Q58999)
Key From To Description Tag Condition FTGroup
ACT_SITE 442 442 /note="Proton acceptor" D
BINDING 272 272 /ligand="Mg(2+)"
BINDING 302 302 /ligand="Mg(2+)"
BINDING 442 442 /ligand="Mg(2+)"

Additional information [?]

Size range 440-505 amino acids
Related rules MF_00809
Fusion Nter: None Cter: None

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