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Annotation rule MF_00562 |
Accession | MF_00562 |
Dates | 31-MAY-2002 (Created) 25-NOV-2019 (Last updated, Version 28) |
Name | Deacylase_DtdA |
Scope | Archaea |
Template | Q9V2R8 (DTDA_PYRAB) |
Triggered by |
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Protein name |
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Gene name |
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Function | D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. |
Catalytic activity | RHEA:13953: a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + H(+) + tRNA
EC 3.1.1.96 |
RHEA:53744: glycyl-tRNA(Ala) + H2O = glycine + H(+) + tRNA(Ala)
EC 3.1.1.96 |
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Cofactor | Zn(2+) Note: Binds 2 Zn(2+) ions per subunit. |
Subunit | Monomer. |
Similarity | Belongs to the DtdA deacylase family. |
Pfam | PF04414; tRNA_deacylase; 1; |
PIRSF | PIRSF016210; UCP016210; 1; |
Size range | 237-524 amino acids |
Related rules | None |
Fusion | None |
Comments | Divergent HALSA not shown in alignment |