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Annotation rule MF_00568 |
General rule information
[?]
Accession |
MF_00568 |
Dates |
2-JUL-2002 (Created) 18-NOV-2019 (Last updated, Version 34) |
Scope |
Bacteria
Archaea
Plastid |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Function |
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. |
Catalytic activity |
RHEA:25888: dihydroxyacetone phosphate + iminosuccinate = H(+) + 2 H2O + phosphate + quinolinate
EC 2.5.1.72
|
Cofactor |
[4Fe-4S] cluster Note: Binds 1 [4Fe-4S] cluster per subunit. |
Pathway |
Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from iminoaspartate: step 1/1. |
case not <OG:Chloroplast>
Subcellular location |
Cytoplasm. |
end case
case <OG:Chloroplast>
Subcellular location |
Plastid, chloroplast. |
end case
Similarity |
Belongs to the quinolinate synthase A family. Type 2 subfamily. |
case not <OG:Chloroplast>
end case
GO:0008987; Molecular function: quinolinate synthetase A activity.
GO:0009435; Biological process: NAD biosynthetic process.
case not <OG:Chloroplast>
end case
case <OG:Chloroplast>
end case
From: NADA_PYRHO (O57767) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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BINDING
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21
|
|
21
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Iminoaspartate
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H
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BINDING
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38
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38
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Iminoaspartate; via amide nitrogen
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|
|
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S
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BINDING
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109
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109
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|
Iminoaspartate
|
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Y
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|
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BINDING
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126
|
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126
|
|
Iminoaspartate
|
|
|
|
S
|
|
|
BINDING
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196
|
|
196
|
|
Iminoaspartate
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|
|
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H
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BINDING
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|
213
|
|
213
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|
Iminoaspartate
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|
|
|
T
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|
|
Additional information
[?]
Size range |
298-377 amino acids |
Related rules |
MF_00567 (NADA); MF_00569 (NADA) |
Fusion |
None |