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Annotation rule MF_00588 |
Accession | MF_00588 |
Dates | 22-OCT-2002 (Created) 18-NOV-2019 (Last updated, Version 20) |
Name | GatE |
Scope | Archaea |
Template | O26803 (GATE_METTH) |
Triggered by |
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Gene name |
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Function | Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. |
Catalytic activity | RHEA:17521: ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate |
Subunit | Heterodimer of GatD and GatE. |
Similarity | Belongs to the GatB/GatE family. GatE subfamily. |
Pfam | PF02938; GAD; 1; |
PF02934; GatB_N; 1; | |
PF02637; GatB_Yqey; 1; | |
TIGRFAMs | TIGR00134; GatE_arch; 1; |
PROSITE | PS01234; GATB; 1; |
Size range | 598-642 amino acids |
Related rules | MF_00121 (GATB) |
Fusion | None |