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| Annotation rule MF_00588 |
General rule information
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| Accession | MF_00588 |
| Dates | 22-OCT-2002 (Created) 18-NOV-2019 (Last updated, Version 20) |
| Name | GatE |
| Scope | Archaea |
| Template | O26803 (GATE_METTH) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. |
| Catalytic activity | RHEA:17521: ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate |
| Subunit | Heterodimer of GatD and GatE. |
| Similarity | Belongs to the GatB/GatE family. GatE subfamily. |
Keywords
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Gene Ontology
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GO:0050567; Molecular function: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity.
GO:0006412; Biological process: translation.
GO:0006412; Biological process: translation.
Cross-references
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| Pfam | PF02938; GAD; 1; |
| PF02934; GatB_N; 1; | |
| PF02637; GatB_Yqey; 1; | |
| TIGRFAMs | TIGR00134; GatE_arch; 1; |
| PROSITE | PS01234; GATB; 1; |
Additional information
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| Size range | 598-642 amino acids |
| Related rules | MF_00121 (GATB) |
| Fusion | None |