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Annotation rule MF_00605
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General rule information [?]

Accession MF_00605
Dates 29-NOV-2002 (Created)
18-NOV-2019 (Last updated, Version 24)
Name TrmD
Scope
Bacteria
Template P0A873 (TRMD_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
TRMD
Protein name
RecName: Full=tRNA (guanine-N(1)-)-methyltransferase;
EC 2.1.1.228;
AltName: Full=M1G-methyltransferase;
AltName: Full=tRNA [GM37] methyltransferase;
Gene name
trmD

Comments [?]

Function Specifically methylates guanosine-37 in various tRNAs.
Catalytic activity RHEA:36899: guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine
EC 2.1.1.228
Subunit Homodimer.
Subcellular location Cytoplasm.
Similarity Belongs to the RNA methyltransferase TrmD family.

Keywords [?]

Cytoplasm
Methyltransferase
Transferase
tRNA processing
S-adenosyl-L-methionine

Gene Ontology [?]

GO:0009019; Molecular function: tRNA (guanine-N1-)-methyltransferase activity.
GO:0006400; Biological process: tRNA modification.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01746; tRNA_m1G_MT; 1;
TIGRFAMs TIGR00088; TrmD; 1;

Features [?]

From: TRMD_ECOLI (P0A873)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     133     138       S-adenosyl-L-methionine binding     [ILVM]-G-[DN]-[YF]-[IV]-[ILVM]  
BINDING     113     113       S-adenosyl-L-methionine; via amide nitrogen     G  

Additional information [?]

Size range 222-361 amino acids
Related rules None
Fusion Nter: None; Cter: <Unknown>


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