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Annotation rule MF_00608 |
Accession | MF_00608 |
Dates | 10-DEC-2002 (Created) 18-NOV-2019 (Last updated, Version 25) |
Name | GTP_cyclohydro_3 |
Scope | Archaea |
Template | Q57609 (GCH3_METJA) |
Triggered by |
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Function | Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity. |
Catalytic activity | RHEA:22468: GTP + 3 H2O = 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + 2 H(+) + 2 phosphate
EC 3.5.4.29 |
Similarity | Belongs to the archaeal-type GTP cyclohydrolase family. |
Pfam | PF05165; GGDN; 1; |
PIRSF | PIRSF009265; GTP_cyclohydro_3; 1; |
Size range | 221-268 amino acids |
Related rules | None |
Fusion | None |