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Annotation rule MF_00608
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General rule information [?]

Accession MF_00608
Dates 10-DEC-2002 (Created)
18-NOV-2019 (Last updated, Version 25)
Name GTP_cyclohydro_3
Scope
Archaea
Template Q57609 (GCH3_METJA)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
GCH3
Protein name
RecName: Full=GTP cyclohydrolase III;
EC 3.5.4.29;
Gene name
gch3

Comments [?]

Function Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Catalytic activity RHEA:22468: GTP + 3 H2O = 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + 2 H(+) + 2 phosphate
EC 3.5.4.29
Similarity Belongs to the archaeal-type GTP cyclohydrolase family.

Keywords [?]


Gene Ontology [?]

GO:0016814; Molecular function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines.

Cross-references [?]

Pfam PF05165; GGDN; 1;
PIRSF PIRSF009265; GTP_cyclohydro_3; 1;

Additional information [?]

Size range 221-268 amino acids
Related rules None
Fusion None