HAMAP rule MF_00608
General rule information
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Accession |
MF_00608 |
Dates |
10-DEC-2002 (Created) 18-NOV-2019 (Last updated, Version 25) |
Propagated annotation
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Identifier, protein and gene names
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Function |
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity. |
Catalytic activity |
RHEA:22468: GTP + 3 H2O = 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + 2 H(+) + 2 phosphate
EC 3.5.4.29
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Similarity |
Belongs to the archaeal-type GTP cyclohydrolase family. |
GO:0016814; Molecular function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines.
Additional information
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Size range |
221-268 amino acids |
Related rules |
None |
Fusion |
None |