HAMAP rule MF_00626

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00626
Accession	MF_00626
Dates	28-FEB-2005 (Created) 01-JUN-2023 (Last updated, Version 16)
Name	Germination_prot
Scope(s)	Bacteria Bacillales Clostridia
Template(s)	P22321; [ Recover all ]
Triggered by	HAMAP; MF_00626 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	GPR
Protein name	RecName: Full=Germination protease; EC=3.4.24.78; AltName: Full=GPR endopeptidase; AltName: Full=Germination proteinase; AltName: Full=Spore protease; Flags: Precursor;
Gene name	Name=gpr;

Comments [?]

FUNCTION	Initiates the rapid degradation of small, acid-soluble proteins during spore germination.
CATALYTIC ACTIVITY	Reaction=Endopeptidase action with P4 Glu or Asp, P1 preferably Glu > Asp, P1' hydrophobic and P2' Ala.; EC=3.4.24.78;
SUBUNIT	Homotetramer.
PTM	Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
SIMILARITY	Belongs to the peptidase A25 family.

Keywords [?]

Gene Ontology [?]

GO:0004222; Molecular function:metalloendopeptidase activity

GO:0006508; Biological process:proteolysis

GO:0009847; Biological process:spore germination

Cross-references [?]

Features [?]

From: GPR_PRIM1 (P22321)

Key

From

Description

Tag

Condition

FTGroup

PROPEP

Nter

CHAIN

Cter

/note="Germination protease"

Additional information [?]