HAMAP rule MF_00626
General rule information
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Accession | MF_00626 |
Dates | 20-MAR-2003 (Created)
1-JUN-2023 (Last updated, Version 19) |
Name | Germination_prot |
Scope(s) |
Bacteria Bacillales Clostridia |
Template(s) | P22321 (GPR_PRIM1); [ Recover all ] |
Triggered by |
HAMAP; MF_00626 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | GPR |
Protein name | RecName: Full=Germination protease; EC=3.4.24.78; AltName: Full=GPR endopeptidase; AltName: Full=Germination proteinase; AltName: Full=Spore protease; Flags: Precursor; |
Gene name | Name=gpr; |
Comments
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FUNCTION | Initiates the rapid degradation of small, acid-soluble proteins during spore germination. |
CATALYTIC ACTIVITY | Reaction=Endopeptidase action with P4 Glu or Asp, P1 preferably Glu > Asp, P1' hydrophobic and P2' Ala.; EC=3.4.24.78; |
SUBUNIT | Homotetramer. |
PTM | Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination. |
SIMILARITY | Belongs to the peptidase A25 family. |
Keywords
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Gene Ontology
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GO:0004222; Molecular function:metalloendopeptidase activity |
GO:0006508; Biological process:proteolysis |
GO:0009847; Biological process:spore germination |
Cross-references
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Pfam | PF03418; Peptidase_A25; 1; |
PIRSF | PIRSF019549; Peptidase_A25; 1; |
NCBIfam | TIGR01441; GPR; 1; |
Features
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From: GPR_PRIM1 (P22321) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
PROPEP | Nter | 15 | ||||||||||
CHAIN | 16 | Cter | /note="Germination protease" |
Additional information
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Size range | 323-372 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |