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Annotation rule MF_00626
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General rule information [?]

Accession MF_00626
Dates 20-MAR-2003 (Created)
18-NOV-2019 (Last updated, Version 17)
Name Germination_prot
Scope
Bacteria; Bacillales
Bacteria; Clostridia
Template P22321 (GPR_BACMQ)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
GPR
Protein name
RecName: Full=Germination protease;
EC 3.4.24.78;
AltName: Full=GPR endopeptidase;
AltName: Full=Germination proteinase;
AltName: Full=Spore protease;
Flags: Precursor;
Gene name
gpr

Comments [?]

Function Initiates the rapid degradation of small, acid-soluble proteins during spore germination.
Catalytic activity Reaction=Endopeptidase action with P4 Glu or Asp, P1 preferably Glu > Asp, P1' hydrophobic and P2' Ala.; EC=3.4.24.78;
Subunit Homotetramer.
Ptm Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
Similarity Belongs to the peptidase A25 family.

Keywords [?]

Hydrolase
Protease
Zymogen

Gene Ontology [?]

GO:0004222; Molecular function: metalloendopeptidase activity.
GO:0006508; Biological process: proteolysis.
GO:0009847; Biological process: spore germination.

Cross-references [?]

Pfam PF03418; Peptidase_A25; 1;
PIRSF PIRSF019549; Peptidase_A25; 1;
TIGRFAMs TIGR01441; GPR; 1;

Features [?]

From: GPR_BACMQ (P22321)
Key     From     To       Description   Tag   Condition   FTGroup
PROPEP     Nter     15                
CHAIN     16     Cter       Germination protease        

Additional information [?]

Size range 323-372 amino acids
Related rules None
Fusion None


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