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HAMAP rule MF_00626

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General rule information [?]

Accession MF_00626
Dates 20-MAR-2003 (Created)
1-JUN-2023 (Last updated, Version 19)
Name Germination_prot
Scope(s) Bacteria
Template(s) P22321 (GPR_PRIM1); [ Recover all ]
Triggered by HAMAP; MF_00626 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier GPR
Protein name RecName: Full=Germination protease;
AltName: Full=GPR endopeptidase;
AltName: Full=Germination proteinase;
AltName: Full=Spore protease;
                 Flags: Precursor;
Gene name Name=gpr;

Comments [?]

FUNCTIONInitiates the rapid degradation of small, acid-soluble proteins during spore germination.
CATALYTIC ACTIVITY Reaction=Endopeptidase action with P4 Glu or Asp, P1 preferably Glu > Asp, P1' hydrophobic and P2' Ala.; EC=;
PTMAutoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
SIMILARITYBelongs to the peptidase A25 family.

Keywords [?]

Gene Ontology [?]

GO:0004222; Molecular function:metalloendopeptidase activity
GO:0006508; Biological process:proteolysis
GO:0009847; Biological process:spore germination

Cross-references [?]

Pfam PF03418; Peptidase_A25; 1;
PIRSF PIRSF019549; Peptidase_A25; 1;
NCBIfam TIGR01441; GPR; 1;

Features [?]

From: GPR_PRIM1 (P22321)
Key From To Description Tag Condition FTGroup
PROPEP Nter 15
CHAIN 16 Cter /note="Germination protease"

Additional information [?]

Size range 323-372 amino acids
Related rules None
Fusion Nter: None Cter: None

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