HAMAP rule MF_00637
General rule information
[?]
Accession | MF_00637 |
Dates | 17-APR-2003 (Created)
1-JUN-2023 (Last updated, Version 20) |
Name | Anti_sigma_F |
Scope(s) |
Bacteria Bacillales Clostridia |
Template(s) | P10728 (SP2AB_BACSU); [ Recover all ] |
Triggered by |
HAMAP; MF_00637 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier | SP2AB |
Protein name | RecName: Full=Anti-sigma F factor; EC=2.7.11.1; AltName: Full=Stage II sporulation protein AB; |
Gene name | Name=spoIIAB; |
Comments
[?]
FUNCTION | Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. |
CATALYTIC ACTIVITY | Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA- COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616, ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1; |
CATALYTIC ACTIVITY | Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060, Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216; EC=2.7.11.1; |
SIMILARITY | Belongs to the anti-sigma-factor family. |
Keywords
[?]
Gene Ontology
[?]
GO:0004672; Molecular function:protein kinase activity |
GO:0010468; Biological process:regulation of gene expression |
GO:0030436; Biological process:asexual sporulation |
Cross-references
[?]
Features
[?]
Additional information
[?]
Size range | 140-151 amino acids |
Related rules |
MF_00638 |
Fusion | Nter: None Cter: None |