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Annotation rule MF_00637
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General rule information [?]

Accession MF_00637
Dates 17-APR-2003 (Created)
18-NOV-2019 (Last updated, Version 19)
Name Anti_sigma_F
Bacteria; Bacillales
Bacteria; Clostridia
Template P10728 (SP2AB_BACSU)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Anti-sigma F factor;
AltName: Full=Stage II sporulation protein AB;
Gene name

Comments [?]

Function Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
Catalytic activity RHEA:17989: ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]
RHEA:46608: ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]
Similarity Belongs to the anti-sigma-factor family.

Keywords [?]

Gene Ontology [?]

GO:0004672; Molecular function: protein kinase activity.
GO:0010468; Biological process: regulation of gene expression.
GO:0030436; Biological process: asexual sporulation.

Cross-references [?]

Pfam PF02518; HATPase_c; 1;
TIGRFAMs TIGR01925; spIIAB; 1;

Additional information [?]

Size range 140-151 amino acids
Related rules MF_00638 (RSBW)
Fusion None