HAMAP rule MF_00658
General rule information
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Accession | MF_00658 |
Dates | 17-JUN-2003 (Created) 1-JUN-2023 (Last updated, Version 35) |
Name | 23SrRNA_methyltr_H |
Scope | Bacteria
Archaea; Euryarchaeota |
Templates | P0A8I8 (RLMH_ECOLI); P0C1V0 (RLMH_STAAU): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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case <OC:Bacteria>
Protein name |
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else case <OC:Archaea>
Protein name |
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end case
Gene name |
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Comments
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Function | Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. |
Catalytic activity | RHEA:42752: pseudouridine(1915) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(3)-methylpseudouridine(1915) in 23S rRNA + S-adenosyl-L-homocysteine
EC 2.1.1.177 |
case <OC:Bacteria>
Subunit | Homodimer. |
end case
Subcellular location | Cytoplasm. |
Similarity | Belongs to the RNA methyltransferase RlmH family. |
Keywords
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Gene Ontology
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GO:0070038; Molecular function: rRNA (pseudouridine-N3-)-methyltransferase activity.
GO:0031167; Biological process: rRNA methylation.
GO:0005737; Cellular component: cytoplasm.
GO:0031167; Biological process: rRNA methylation.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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Pfam | PF02590; SPOUT_MTase; 1; |
PIRSF | PIRSF004505; MT_bac; 1; |
NCBIfam | TIGR00246; tRNA_RlmH_YbeA; 1; |
Features
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From: RLMH_ECOLI (P0A8I8) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING (Optional) | 122 | 127 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | [LIVFM]-[GAST]-x-[LIM]-x-[LMFYW] | ||||||||
BINDING (Optional) | 72 | 72 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | [LI] | ||||||||
BINDING (Optional) | 103 | 103 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | [GA] |
Additional information
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Size range | 120-210 amino acids |
Related rules | None |
Fusion | None |