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HAMAP rule MF_00661

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General rule information [?]

PURL https://purl.expasy.org/hamap/rule/MF_00661
Accession MF_00661
Dates 28-FEB-2005 (Created)
02-SEP-2024 (Last updated, Version 23)
Name DEAD_helicase_RhlB
Scope(s) Bacteria
Pseudomonadota
Template(s) P0A8J8; [ Recover all ]
Triggered by HAMAP; MF_00661 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RHLB
Protein name RecName: Full=ATP-dependent RNA helicase RhlB;
                 EC=3.6.4.13;
Gene name Name=rhlB;

Comments [?]

FUNCTIONDEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.
CATALYTIC ACTIVITY Reaction=ATP + H2O = ADP + phosphate + H(+); Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
case <OC:Gammaproteobacteria>
SUBUNITComponent of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
end case
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the DEAD box helicase family. RhlB subfamily.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0003724; Molecular function:RNA helicase activity
GO:0003723; Molecular function:RNA binding
GO:0006401; Biological process:RNA catabolic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF00270; DEAD; 1;
Pfam PF00271; Helicase_C; 1;
PROSITE PS00039; DEAD_ATP_HELICASE; 1;
PROSITE PS51192; HELICASE_ATP_BIND_1; 1;
PROSITE PS51194; HELICASE_CTER; 1;
PROSITE PS51195; Q_MOTIF; 1;

Features [?]


Additional information [?]

Size range 360-600 amino acids
Related rules None
Fusion Nter: None Cter: None



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