HAMAP rule MF_00661
General rule information
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| Accession | MF_00661 |
| Dates | 26-JUN-2003 (Created) 26-JAN-2023 (Last updated, Version 25) |
| Name | DEAD_helicase_RhlB |
| Scope | Bacteria; Pseudomonadota |
| Template | P0A8J8 (RHLB_ECOLI) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA. |
| Catalytic activity | RHEA:13065: ATP + H2O = ADP + H(+) + phosphate
EC 3.6.4.13 |
case <OC:Gammaproteobacteria>
| Subunit | Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. |
end case
| Subcellular location | Cytoplasm. |
| Similarity | Belongs to the DEAD box helicase family. RhlB subfamily. |
Keywords
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Gene Ontology
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GO:0005524; Molecular function: ATP binding.
GO:0003724; Molecular function: RNA helicase activity.
GO:0003723; Molecular function: RNA binding.
GO:0006401; Biological process: RNA catabolic process.
GO:0005737; Cellular component: cytoplasm.
GO:0003724; Molecular function: RNA helicase activity.
GO:0003723; Molecular function: RNA binding.
GO:0006401; Biological process: RNA catabolic process.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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| Pfam | PF00270; DEAD; 1; |
| PF00271; Helicase_C; 1; | |
| PROSITE | PS00039; DEAD_ATP_HELICASE; 1; |
| PS51192; HELICASE_ATP_BIND_1; 1; trigger=PRU00541; | |
| PS51194; HELICASE_CTER; 1; trigger=PRU00542; | |
| PS51195; Q_MOTIF; 1; trigger=PRU00552; |
Additional information
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| Size range | 360-600 amino acids |
| Related rules | None |
| Fusion | None |