HAMAP rule MF_00661
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00661 |
| Accession | MF_00661 |
| Dates | 28-FEB-2005 (Created)
02-SEP-2024 (Last updated, Version 23) |
| Name | DEAD_helicase_RhlB |
| Scope(s) |
Bacteria Pseudomonadota |
| Template(s) | P0A8J8; [ Recover all ] |
| Triggered by |
HAMAP; MF_00661 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RHLB |
| Protein name | RecName: Full=ATP-dependent RNA helicase RhlB; EC=3.6.4.13; |
| Gene name | Name=rhlB; |
Comments
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| FUNCTION | DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. |
| CATALYTIC ACTIVITY | Reaction=ATP + H2O = ADP + phosphate + H(+); Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13; |
| case <OC:Gammaproteobacteria> | |
| SUBUNIT | Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. |
| end case | |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the DEAD box helicase family. RhlB subfamily. |
Keywords
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Gene Ontology
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| GO:0005524; Molecular function:ATP binding |
| GO:0003724; Molecular function:RNA helicase activity |
| GO:0003723; Molecular function:RNA binding |
| GO:0006401; Biological process:RNA catabolic process |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF00270; DEAD; 1; |
| Pfam | PF00271; Helicase_C; 1; |
| PROSITE | PS00039; DEAD_ATP_HELICASE; 1; |
| PROSITE | PS51192; HELICASE_ATP_BIND_1; 1; |
| PROSITE | PS51194; HELICASE_CTER; 1; |
| PROSITE | PS51195; Q_MOTIF; 1; |
Features
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Additional information
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| Size range | 360-600 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |