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HAMAP rule MF_00687

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General rule information [?]

Accession MF_00687
Dates 23-JUL-2003 (Created)
19-NOV-2022 (Last updated, Version 26)
Name KduI
Templates Q46938 (KDUI_ECOLI); Q05529 (KDUI_DICD3); P50843 (KDUI_BACSU): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase;
AltName: Full=5-keto-4-deoxyuronate isomerase;
AltName: Full=DKI isomerase;
Gene name

Comments [?]

Function Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
Catalytic activity RHEA:23896: 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate
case <FTGroup:1>
Cofactor Zn(2+)
Note: Binds 1 zinc ion per subunit.
end case
Pathway Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 4/5.
case <OC:Escherichia>
Subunit Homohexamer.
end case
Similarity Belongs to the KduI family.

Keywords [?]

case <FTGroup:1>
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0008270; Molecular function: zinc ion binding.
end case
GO:0008697; Molecular function: 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity.
GO:0045490; Biological process: pectin catabolic process.

Cross-references [?]

Pfam PF04962; KduI; 1;

Features [?]

From: KDUI_ECOLI (Q46938)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     196     196       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     H   1
BINDING     198     198       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     H   1
BINDING     203     203       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     E   1
BINDING     245     245       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     H   1

Additional information [?]

Size range 274-292 amino acids
Related rules None
Fusion None