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Annotation rule MF_00688 |
Accession | MF_00688 |
Dates | 24-JUL-2003 (Created) 18-NOV-2019 (Last updated, Version 23) |
Name | Leu_Phe_trans |
Scope | Bacteria |
Template | P0A8P1 (LFTR_ECOLI) |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. |
Catalytic activity | RHEA:12340: L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = H(+) + N-terminal L-leucyl-L-lysyl-[protein] + tRNA(Leu)
EC 2.3.2.6 |
RHEA:50416: L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = H(+) + N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu)
EC 2.3.2.6 |
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RHEA:43632: an N-terminal L-alpha-aminoacyl-[protein] + L-phenylalanyl-tRNA(Phe) = an N-terminal L-phenylalanyl-L-alpha-aminoacyl-[protein] + tRNA(Phe)
EC 2.3.2.6 |
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Subcellular location | Cytoplasm. |
Similarity | Belongs to the L/F-transferase family. |
Size range | 191-274 amino acids |
Related rules | None |
Fusion | None |