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HAMAP rule MF_00689

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General rule information [?]

Accession MF_00689
Dates 25-JUL-2003 (Created)
28-JUL-2023 (Last updated, Version 23)
Name Bpt
Scope(s) Bacteria
Template(s) Q8DAR7 (BPT_VIBVU); Q8UG81 (BPT_AGRFC); Q983E4 (BPT_RHILO); [ Recover all ]
Triggered by HAMAP; MF_00689 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier BPT
Protein name RecName: Full=Aspartate/glutamate leucyltransferase;
Gene name Name=bpt;

Comments [?]

FUNCTIONFunctions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
CATALYTIC ACTIVITY Reaction=L-leucyl-tRNA(Leu) + N-terminal L-glutamyl-[protein] = H(+) + N-terminal L-leucyl-L-glutamyl-[protein] + tRNA(Leu); Xref=Rhea:RHEA:50412, Rhea:RHEA-COMP:9613, Rhea:RHEA-COMP:9622, Rhea:RHEA-COMP:12664, Rhea:RHEA-COMP:12668, ChEBI:CHEBI:15378, ChEBI:CHEBI:64721, ChEBI:CHEBI:78442, ChEBI:CHEBI:78494, ChEBI:CHEBI:133041; EC=;
CATALYTIC ACTIVITY Reaction=L-leucyl-tRNA(Leu) + N-terminal L-aspartyl-[protein] = H(+) + N-terminal L-leucyl-L-aspartyl-[protein] + tRNA(Leu); Xref=Rhea:RHEA:50420, Rhea:RHEA-COMP:9613, Rhea:RHEA-COMP:9622, Rhea:RHEA-COMP:12669, Rhea:RHEA-COMP:12674, ChEBI:CHEBI:15378, ChEBI:CHEBI:64720, ChEBI:CHEBI:78442, ChEBI:CHEBI:78494, ChEBI:CHEBI:133042; EC=;
SIMILARITYBelongs to the R-transferase family. Bpt subfamily.

Keywords [?]

Gene Ontology [?]

GO:0008914; Molecular function:leucyl-tRNA--protein transferase activity
GO:0030163; Biological process:protein catabolic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF04377; ATE_C; 1;
Pfam PF04376; ATE_N; 1;
PIRSF PIRSF037208; ATE_pro_prd; 1;

Features [?]

Additional information [?]

Size range 200-325 amino acids
Related rules None
Fusion Nter: None Cter: None

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