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HAMAP rule MF_00697

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General rule information [?]

PURL https://purl.expasy.org/hamap/rule/MF_00697
Accession MF_00697
Dates 28-FEB-2005 (Created)
27-OCT-2025 (Last updated, Version )
Name MNIO_HvfB
Scope(s) Bacteria
Template(s) Q4QL35; [ Recover all ]
Triggered by HAMAP; MF_00697 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

case <OS:Haemophilus influenzae>
Identifier HVFB
Protein name RecName: Full=Multinuclear non-heme iron-dependent oxidase HvfB;
                 Short=MNIO HvfB;
Gene name Name=hvfB;
else
Identifier Ynnn
Protein name RecName: Full=Multinuclear non-heme iron-dependent oxidase ;
end case

Comments [?]

case <OS:Haemophilus influenzae>
FUNCTIONOxidase involved in the biosynthesis of ribosomally synthesized, post-translationally modified peptide natural products (RiPPs). HvfB is involved in the biosynthesis of the virulence factor peptide HvfA (oxazolin).
else
FUNCTIONOxidase involved in the biosynthesis of ribosomally synthesized, post-translationally modified peptide natural products (RiPPs).
end case
case <FTGroup:1> and <FTGroup:2>
COFACTOR Name=Fe cation; Xref=ChEBI:CHEBI:24875; Note=The active species is a mixed-valent Fe(II)Fe(III) cluster.
end case
SIMILARITYBelongs to the multinuclear non-heme iron-dependent oxidase (MNIO) superfamily. HvfB family.

Keywords [?]

case <FTGroup:1> or <FTGroup:2> or <FTGroup:3>
Iron
Metal-binding
end case

Gene Ontology [?]

case <FTGroup:1> or <FTGroup:2> or <FTGroup:3>
GO:0005506; Molecular function:iron ion binding
end case

Cross-references [?]

Pfam PF05114; MbnB_TglH_ChrH; 1;
NCBIfam NF003818; PRK05409.1; 1;

Features [?]

From: HVFB_HAEI8 (Q4QL35)
Key From To Description Tag Condition FTGroup
BINDING 70 70 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="#1"
/ligand_note="catalytic"		 H 1
BINDING 105 105 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="#1"
/ligand_note="catalytic"		 H 1
BINDING 149 149 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="#1"
/ligand_note="catalytic"		 E 1
BINDING 149 149 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="#2"
/ligand_note="catalytic"		 E 2
BINDING 182 182 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="#2"
/ligand_note="catalytic"		 D 2
BINDING 185 185 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="#3"		 N 3
BINDING 214 214 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="#2"
/ligand_note="catalytic"		 H 2
BINDING 252 252 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="#3"		 D 3
BINDING 254 254 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="#3"		 H 3
BINDING 282 282 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="#2"
/ligand_note="catalytic"		 E 2

Additional information [?]

Size range 273-309 amino acids
Related rules None
Fusion Nter: None Cter: <Unknown>



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