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| Annotation rule MF_00705 |
General rule information
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| Accession | MF_00705 |
| Dates | 1-SEP-2003 (Created) 18-NOV-2019 (Last updated, Version 23) |
| Name | IMP_cyclohydrol |
| Scope | Archaea |
| Template | Q58043 (PURO_METJA) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP. |
| Catalytic activity | RHEA:18445: H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
EC 3.5.4.10 |
| Pathway | Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1. |
| Similarity | Belongs to the archaeal IMP cyclohydrolase family. |
Keywords
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Gene Ontology
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GO:0003937; Molecular function: IMP cyclohydrolase activity.
GO:0006189; Biological process: 'de novo' IMP biosynthetic process.
GO:0006189; Biological process: 'de novo' IMP biosynthetic process.
Cross-references
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| Pfam | PF07826; IMP_cyclohyd; 1; |
| PIRSF | PIRSF004866; IMP_cclhdr_arch; 1; |
| TIGRFAMs | TIGR01922; PurO_arch; 1; |
Additional information
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| Size range | 190-230 amino acids |
| Related rules | None |
| Fusion | None |