HAMAP rule MF_00705

General rule information [?]

Accession	MF_00705
Dates	1-SEP-2003 (Created) 2-SEP-2024 (Last updated, Version 25)
Name	IMP_cyclohydrol
Scope(s)	Archaea
Template(s)	Q58043 (PURO_METJA); [ Recover all ]
Triggered by	HAMAP; MF_00705 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	PURO
RecName: Full=IMP cyclohydrolase;<br />                  EC=<a href="https://enzyme.expasy.org/EC/3.5.4.10">3.5.4.10</a>;<br /> AltName: Full=IMP synthase;<br /> AltName: Full=Inosinicase;
Gene name	Name=purO;

Comments [?]

FUNCTION	Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP.
CATALYTIC ACTIVITY	Reaction=IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4- carboxamide; Xref=Rhea:RHEA:18445, ChEBI:CHEBI:15377, ChEBI:CHEBI:58053, ChEBI:CHEBI:58467; EC=3.5.4.10;
PATHWAY	Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.
SIMILARITY	Belongs to the archaeal IMP cyclohydrolase family.

Keywords [?]

Gene Ontology [?]

GO:0003937; Molecular function:IMP cyclohydrolase activity

GO:0006189; Biological process:'de novo' IMP biosynthetic process

Cross-references [?]

Features [?]

Additional information [?]