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Annotation rule MF_00705
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General rule information [?]

Accession MF_00705
Dates 1-SEP-2003 (Created)
18-NOV-2019 (Last updated, Version 23)
Name IMP_cyclohydrol
Scope
Archaea
Template Q58043 (PURO_METJA)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PURO
Protein name
RecName: Full=IMP cyclohydrolase;
EC 3.5.4.10;
AltName: Full=IMP synthase;
AltName: Full=Inosinicase;
Gene name
purO

Comments [?]

Function Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.
Catalytic activity RHEA:18445: H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
EC 3.5.4.10
Pathway Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.
Similarity Belongs to the archaeal IMP cyclohydrolase family.

Keywords [?]


Gene Ontology [?]

GO:0003937; Molecular function: IMP cyclohydrolase activity.
GO:0006189; Biological process: 'de novo' IMP biosynthetic process.

Cross-references [?]

Pfam PF07826; IMP_cyclohyd; 1;
PIRSF PIRSF004866; IMP_cclhdr_arch; 1;
TIGRFAMs TIGR01922; PurO_arch; 1;

Additional information [?]

Size range 190-230 amino acids
Related rules None
Fusion None