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Annotation rule MF_00708
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General rule information [?]

Accession MF_00708
Dates 9-SEP-2003 (Created)
15-MAY-2020 (Last updated, Version 28)
Name Fumarate_red_C
Scope
Bacteria; Gammaproteobacteria
Bacteria; Mycobacterium
Template P0A8Q0 (FRDC_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
FRDC
case <OC:Enterobacterales>
Protein name
RecName: Full=Fumarate reductase subunit C;
AltName: Full=Fumarate reductase 15 kDa hydrophobic protein;
AltName: Full=Quinol-fumarate reductase subunit C;
Short=QFR subunit C;
else
Protein name
RecName: Full=Fumarate reductase subunit C;
AltName: Full=Quinol-fumarate reductase subunit C;
Short=QFR subunit C;
end case
Gene name
frdC

Comments [?]

case <OC:Enterobacterales>
Function Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
else
Function Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
end case
Subunit Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
Subcellular location Cell inner membrane; Multi-pass membrane protein.
end case
Similarity Belongs to the FrdC family.

Keywords [?]

case defined <Property:Membrane> and <Property:Membrane=2>
end case

Gene Ontology [?]

GO:0005886; Cellular component: plasma membrane.
GO:0045284; Cellular component: plasma membrane fumarate reductase complex.
GO:0000104; Molecular function: succinate dehydrogenase activity.

Cross-references [?]

Pfam PF02300; Fumarate_red_C; 1;

Computed features [?]

General Transmembrane; -; 3; trigger=yes;

Additional information [?]

Size range 126-132 amino acids
Related rules None
Fusion None