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| Annotation rule MF_00731 |
General rule information
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| Accession | MF_00731 |
| Dates | 20-NOV-2003 (Created) 18-NOV-2019 (Last updated, Version 27) |
| Name | MenE |
| Scope | Bacteria
Archaea |
| Template | P23971 (MENE_BACSU) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA). |
| Catalytic activity | RHEA:17009: 2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP + diphosphate
EC 6.2.1.26 |
| Pathway | Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 5/7. |
case not <OC:Cyanobacteria>
| Pathway | Quinol/quinone metabolism; menaquinone biosynthesis. |
else case <OC:Cyanobacteria>
| Pathway | Cofactor biosynthesis; phylloquinone biosynthesis. |
end case
| Similarity | Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily. |
Keywords
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case not <OC:Cyanobacteria>
end case
Gene Ontology
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GO:0008756; Molecular function: o-succinylbenzoate-CoA ligase activity.
case not <OC:Cyanobacteria>
GO:0009234; Biological process: menaquinone biosynthetic process.
else case <OC:Cyanobacteria>
GO:0042372; Biological process: phylloquinone biosynthetic process.
end case
Cross-references
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| Pfam | PF00501; AMP-binding; 1; |
| PF13193; AMP-binding_C; 1; | |
| TIGRFAMs | TIGR01923; MenE; 1; |
| PROSITE | PS00455; AMP_BINDING; 1; |
Additional information
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| Size range | 438-514 amino acids |
| Related rules | None |
| Fusion | None |