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Annotation rule MF_00731
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General rule information [?]

Accession MF_00731
Dates 20-NOV-2003 (Created)
18-NOV-2019 (Last updated, Version 27)
Name MenE
Scope
Bacteria
Archaea
Template P23971 (MENE_BACSU)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MENE
Protein name
RecName: Full=2-succinylbenzoate--CoA ligase;
EC 6.2.1.26;
AltName: Full=o-succinylbenzoyl-CoA synthetase;
Short=OSB-CoA synthetase;
Gene name
menE

Comments [?]

Function Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
Catalytic activity RHEA:17009: 2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP + diphosphate
EC 6.2.1.26
Pathway Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 5/7.
case not <OC:Cyanobacteria>
Pathway Quinol/quinone metabolism; menaquinone biosynthesis.
else case <OC:Cyanobacteria>
Pathway Cofactor biosynthesis; phylloquinone biosynthesis.
end case
Similarity Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.

Keywords [?]

case not <OC:Cyanobacteria>
end case

Gene Ontology [?]

GO:0008756; Molecular function: o-succinylbenzoate-CoA ligase activity.
case not <OC:Cyanobacteria>
GO:0009234; Biological process: menaquinone biosynthetic process.
else case <OC:Cyanobacteria>
GO:0042372; Biological process: phylloquinone biosynthetic process.
end case

Cross-references [?]

Pfam PF00501; AMP-binding; 1;
PF13193; AMP-binding_C; 1;
TIGRFAMs TIGR01923; MenE; 1;
PROSITE PS00455; AMP_BINDING; 1;

Additional information [?]

Size range 438-514 amino acids
Related rules None
Fusion None