HAMAP rule MF_00740

General rule information [?]

Accession	MF_00740
Dates	26-NOV-2003 (Created) 1-JUN-2023 (Last updated, Version 29)
Name	Phosphopentomut
Scope(s)	Bacteria
Template(s)	P0A6K6 (DEOB_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_00740 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	DEOB
Protein name	RecName: Full=Phosphopentomutase; EC=5.4.2.7; AltName: Full=Phosphodeoxyribomutase;
Gene name	Name=deoB;

Comments [?]

FUNCTION	Phosphotransfer between the C1 and C5 carbon atoms of pentose.
CATALYTIC ACTIVITY	Reaction=alpha-D-ribose 1-phosphate = D-ribose 5-phosphate; Xref=Rhea:RHEA:18793, ChEBI:CHEBI:57720, ChEBI:CHEBI:78346; EC=5.4.2.7;
CATALYTIC ACTIVITY	Reaction=2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-D-ribose 5- phosphate; Xref=Rhea:RHEA:27658, ChEBI:CHEBI:57259, ChEBI:CHEBI:62877;
PATHWAY	Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 1/3.
COFACTOR	Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Note=Binds 1 or 2 manganese ions.;
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the phosphopentomutase family.

Keywords [?]

Gene Ontology [?]

GO:0030145; Molecular function:manganese ion binding

GO:0008973; Molecular function:phosphopentomutase activity

GO:0009264; Biological process:deoxyribonucleotide catabolic process

GO:0009166; Biological process:nucleotide catabolic process

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam	PF01676; Metalloenzyme; 1;
NCBIfam	TIGR01696; DeoB; 1;

Features [?]

From: DEOB_ECOLI (P0A6K6)

Key

From

Description

Tag

Condition

FTGroup

BINDING