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Annotation rule MF_00740
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General rule information [?]

Accession MF_00740
Dates 26-NOV-2003 (Created)
18-NOV-2019 (Last updated, Version 26)
Name Phosphopentomut
Scope
Bacteria
Template P0A6K6 (DEOB_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
DEOB
Protein name
RecName: Full=Phosphopentomutase;
EC 5.4.2.7;
AltName: Full=Phosphodeoxyribomutase;
Gene name
deoB

Comments [?]

Function Phosphotransfer between the C1 and C5 carbon atoms of pentose.
Catalytic activity RHEA:18793: alpha-D-ribose 1-phosphate = D-ribose 5-phosphate
EC 5.4.2.7
RHEA:27658: 2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-D-ribose 5-phosphate
Pathway Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 1/3.
Cofactor Mn(2+)
Note: Binds 1 or 2 manganese ions.
Subcellular location Cytoplasm.
Similarity Belongs to the phosphopentomutase family.

Keywords [?]

case <FT:6>
end case
case <FTGroup:1>
end case

Gene Ontology [?]

GO:0030145; Molecular function: manganese ion binding.
GO:0008973; Molecular function: phosphopentomutase activity.
GO:0009264; Biological process: deoxyribonucleotide catabolic process.
GO:0009166; Biological process: nucleotide catabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01676; Metalloenzyme; 1;
TIGRFAMs TIGR01696; DeoB; 1;

Features [?]

From: DEOB_ECOLI (P0A6K6)
Key     From     To       Description   Tag   Condition   FTGroup
METAL     10     10       Manganese     D   1
METAL     311     311       Manganese     H   1
METAL     347     347       Manganese     D   1
METAL     348     348       Manganese     H   1
METAL     359     359       Manganese     H   1
case <OC:Escherichia> or <OC:Shigella>
MOD_RES     287     287       N6-acetyllysine     K  
end case

Additional information [?]

Size range 388-418 amino acids
Related rules None
Fusion None