HAMAP rule MF_00753
General rule information
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| Accession | MF_00753 |
| Dates | 11-MAR-2004 (Created)
7-MAY-2024 (Last updated, Version 25) |
| Name | Glycerol3P_GlpB |
| Scope(s) |
Bacteria Pseudomonadota Archaea Halobacteria |
| Template(s) | P13033 (GLPB_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00753 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | GLPB |
| case <OC:Bacteria> | |
| Protein name | RecName: Full=Anaerobic glycerol-3-phosphate dehydrogenase subunit B; Short=Anaerobic G-3-P dehydrogenase subunit B; Short=Anaerobic G3Pdhase B; EC=1.1.5.3; |
| end case | |
| case <OC:Archaea> | |
| Protein name | RecName: Full=Probable anaerobic glycerol-3-phosphate dehydrogenase subunit B; Short=Anaerobic G-3-P dehydrogenase subunit B; Short=Anaerobic G3Pdhase B; EC=1.1.5.3; |
| end case | |
| Gene name | Name=glpB; |
Comments
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| case <OC:Bacteria> | |
| FUNCTION | Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor. |
| end case | |
| CATALYTIC ACTIVITY | Reaction=a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate; Xref=Rhea:RHEA:18977, ChEBI:CHEBI:24646, ChEBI:CHEBI:57597, ChEBI:CHEBI:57642, ChEBI:CHEBI:132124; EC=1.1.5.3; |
| COFACTOR | Name=FMN; Xref=ChEBI:CHEBI:58210; |
| PATHWAY | Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. |
| case <OC:Bacteria> | |
| SUBUNIT | Composed of a catalytic GlpA/B dimer and of membrane bound GlpC. |
| end case | |
| SIMILARITY | Belongs to the anaerobic G-3-P dehydrogenase subunit B family. |
Keywords
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Gene Ontology
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| GO:0004368; Molecular function:glycerol-3-phosphate dehydrogenase (quinone) activity | |
| case <OCellular component:Bacteria> | |
| GO:0019563; Biological process:glycerol catabolic process | |
| end case | |
Cross-references
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| Pfam | PF00890; FAD_binding_2; 1; |
| PIRSF | PIRSF000141; Anaerobic_G3P_dh; 1; |
| NCBIfam | TIGR03378; Glycerol3P_GlpB; 1; |
Features
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Additional information
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| Size range | 419-455 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |