HAMAP rule MF_00766
General rule information
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Accession | MF_00766 |
Dates | 8-APR-2004 (Created) 1-JUN-2023 (Last updated, Version 37) |
Name | PGT_MtgA |
Scope | Bacteria |
Templates | P46022 (MTGA_ECOLI); Q48465 (MTGA_KLEOX): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. |
Catalytic activity | RHEA:23708: [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)
EC 2.4.1.129 |
Pathway | Cell wall biogenesis; peptidoglycan biosynthesis. |
case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
Subcellular location | Cell inner membrane; Single-pass membrane protein. |
else
Subcellular location | Cell membrane; Single-pass membrane protein. |
end case
Similarity | Belongs to the glycosyltransferase 51 family. |
Keywords
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case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
end case
Cell membrane
Cell shape
Cell wall biogenesis/degradation
Glycosyltransferase
Membrane
Peptidoglycan synthesis
Transferase
Transmembrane
Transmembrane helix
Cell shape
Cell wall biogenesis/degradation
Glycosyltransferase
Membrane
Peptidoglycan synthesis
Transferase
Transmembrane
Transmembrane helix
Gene Ontology
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GO:0008955; Molecular function: peptidoglycan glycosyltransferase activity.
GO:0009252; Biological process: peptidoglycan biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
GO:0009252; Biological process: peptidoglycan biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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Computed features
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General | Transmembrane; -; 1; trigger=yes; |
Additional information
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Size range | 190-300 amino acids |
Related rules | None |
Fusion | None |