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Annotation rule MF_00766 |
General rule information
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Accession |
MF_00766 |
Dates |
8-APR-2004 (Created) 3-NOV-2020 (Last updated, Version 35) |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=Biosynthetic peptidoglycan transglycosylase;
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EC 2.4.1.129;
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AltName:
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Full=Glycan polymerase;
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AltName:
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Full=Peptidoglycan glycosyltransferase MtgA;
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Short=PGT;
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Function |
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. |
Catalytic activity |
RHEA:23708: [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)
EC 2.4.1.129
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Pathway |
Cell wall biogenesis; peptidoglycan biosynthesis. |
case <OC:Proteobacteria> or (defined <Property:Membrane> and <Property:Membrane=2>)
Subcellular location |
Cell inner membrane; Single-pass membrane protein. |
else
Subcellular location |
Cell membrane; Single-pass membrane protein. |
end case
Similarity |
Belongs to the glycosyltransferase 51 family. |
case <OC:Proteobacteria> or (defined <Property:Membrane> and <Property:Membrane=2>)
end case
GO:0008955; Molecular function: peptidoglycan glycosyltransferase activity.
GO:0009252; Biological process: peptidoglycan biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
General |
Transmembrane; -; 1; trigger=yes; |
Additional information
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Size range |
190-300 amino acids |
Related rules |
None |
Fusion |
None |