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Annotation rule MF_00767
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General rule information [?]

Accession MF_00767
Dates 6-APR-2004 (Created)
18-NOV-2019 (Last updated, Version 22)
Name Arg_catab_AstE
Scope
Bacteria; Proteobacteria
Templates P76215 (ASTE_ECOLI); Q7NU26 (ASTE_CHRVO); Q87Q40 (ASTE_VIBPA): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ASTE
Protein name
RecName: Full=Succinylglutamate desuccinylase;
EC 3.5.1.96;
Gene name
astE

Comments [?]

Function Transforms N(2)-succinylglutamate into succinate and glutamate.
Catalytic activity RHEA:15169: H2O + N-succinyl-L-glutamate = L-glutamate + succinate
EC 3.5.1.96
case <FTGroup:1>
Cofactor Zn(2+)
Note: Binds 1 zinc ion per subunit.
end case
Pathway Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 5/5.
Similarity Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.

Keywords [?]

Arginine metabolism
Hydrolase
case <FTGroup:1>
Zinc
Metal-binding
end case

Gene Ontology [?]

GO:0016788; Molecular function: hydrolase activity, acting on ester bonds.
case <FTGroup:1>
GO:0008270; Molecular function: zinc ion binding.
end case
GO:0019544; Biological process: arginine catabolic process to glutamate.

Cross-references [?]

Pfam PF04952; AstE_AspA; 1;
PIRSF PIRSF017020; AstE; 1;
TIGRFAMs TIGR03242; Arg_catab_astE; 1;

Features [?]

From: ASTE_CHRVO (Q7NU26)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     214     214             E  
METAL     56     56       Zinc     H   1
METAL     59     59       Zinc     E   1
METAL     149     149       Zinc     H   1

Additional information [?]

Size range 322-351 amino acids
Related rules None
Fusion None


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