HAMAP rule MF_00776

General rule information [?]

Accession	MF_00776
Dates	25-APR-2004 (Created) 19-NOV-2022 (Last updated, Version 21)

Name

GyaR

Scope

Archaea

Templates

Q9C4M5 (GYAR_THELN); O58320 (GYAR_PYRHO): [Recover all]

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

GYAR

Protein name

RecName:		Full=Glyoxylate reductase;
		EC 1.1.1.26;

Gene name

gyaR

Comments [?]

Catalytic activity	RHEA:18229: glycolate + NAD(+) = glyoxylate + H(+) + NADH EC 1.1.1.26
Subunit	Homodimer.
Subcellular location	Cytoplasm.
Similarity	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily.

Keywords [?]

Gene Ontology [?]

GO:0047964; Molecular function: glyoxylate reductase (NAD+) activity.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Features [?]

From: GYAR_THELN (Q9C4M5)

Key From To Description Tag Condition FTGroup

BINDING 158 161 /ligand="NADP(+)" /ligand_id="ChEBI:CHEBI:58349 [FLM]-G-R-I

BINDING (Optional) 180 182 /ligand="NADP(+)" /ligand_id="ChEBI:CHEBI:58349 S-R-[ST]

BINDING 239 241 /ligand="NADP(+)" /ligand_id="ChEBI:CHEBI:58349 [ITV]-x-R

BINDING 288 290 /ligand="NADP(+)" /ligand_id="ChEBI:CHEBI:58349 H-x-[AG]

ACT_SITE 241 241 R

ACT_SITE 270 270 E

ACT_SITE 288 288 Proton donor H

Additional information [?]