HAMAP rule MF_00776
General rule information
[?]
Accession |
MF_00776 |
Dates |
25-APR-2004 (Created) 19-NOV-2022 (Last updated, Version 21) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Catalytic activity |
RHEA:18229: glycolate + NAD(+) = glyoxylate + H(+) + NADH
EC 1.1.1.26
|
Subunit |
Homodimer. |
Subcellular location |
Cytoplasm. |
Similarity |
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily. |
GO:0047964; Molecular function: glyoxylate reductase (NAD+) activity.
GO:0005737; Cellular component: cytoplasm.
From: GYAR_THELN (Q9C4M5) |
Key
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From
|
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To
|
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Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
BINDING
|
|
158
|
|
161
|
|
/ligand="NADP(+)" /ligand_id="ChEBI:CHEBI:58349
|
|
|
|
[FLM]-G-R-I
|
|
|
BINDING (Optional)
|
|
180
|
|
182
|
|
/ligand="NADP(+)" /ligand_id="ChEBI:CHEBI:58349
|
|
|
|
S-R-[ST]
|
|
|
BINDING
|
|
239
|
|
241
|
|
/ligand="NADP(+)" /ligand_id="ChEBI:CHEBI:58349
|
|
|
|
[ITV]-x-R
|
|
|
BINDING
|
|
288
|
|
290
|
|
/ligand="NADP(+)" /ligand_id="ChEBI:CHEBI:58349
|
|
|
|
H-x-[AG]
|
|
|
ACT_SITE
|
|
241
|
|
241
|
|
|
|
|
|
R
|
|
|
ACT_SITE
|
|
270
|
|
270
|
|
|
|
|
|
E
|
|
|
ACT_SITE
|
|
288
|
|
288
|
|
Proton donor
|
|
|
|
H
|
|
|
Additional information
[?]
Size range |
331-339 amino acids |
Related rules |
None |
Fusion |
None |