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HAMAP rule MF_00786

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General rule information [?]

Accession MF_00786
Dates 24-MAY-2004 (Created)
1-JUN-2023 (Last updated, Version 23)
Name CbiT
Templates O26249 (CBIT_METTH); Q05632 (CBIT_SALTY); O87694 (CBIET_PRIMG): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating);
Gene name

Comments [?]

Function Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
Catalytic activity RHEA:36067: Co-precorrin-6B + S-adenosyl-L-methionine = Co-precorrin-7 + CO2 + S-adenosyl-L-homocysteine
Pathway Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 8/10.
Similarity Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.

Keywords [?]

Gene Ontology [?]

GO:0008168; Molecular function: methyltransferase activity.
GO:0046140; Biological process: corrin biosynthetic process.

Cross-references [?]

Pfam PF08241; Methyltransf_11; 1;
NCBIfam TIGR02469; CbiT; 1;

Features [?]

From: CBIT_METTH (O26249)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     41     45       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     G-x-[GC]-[TS]-G  
BINDING     17     17       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     T  
BINDING     62     62       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     [DE]  
BINDING     91     91       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     [AVG]  

Additional information [?]

Size range 163-202 amino acids
Related rules None
Fusion None