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Annotation rule MF_00811
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General rule information [?]

Accession MF_00811
Dates 30-JUN-2005 (Created)
21-JAN-2020 (Last updated, Version 23)
Name DapD
Scope
Bacteria
Templates P56220 (DAPD_UNKP); P0A9D8 (DAPD_ECOLI); Q8X8Y7 (DAPD_ECO57): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
DAPD
Protein name
RecName: Full=2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase;
EC 2.3.1.117;
AltName: Full=Tetrahydrodipicolinate N-succinyltransferase;
Short=THDP succinyltransferase;
Short=THP succinyltransferase;
Short=Tetrahydropicolinate succinylase;
Gene name
dapD

Comments [?]

Catalytic activity RHEA:17325: (S)-2,3,4,5-tetrahydrodipicolinate + H2O + succinyl-CoA = (S)-2-succinylamino-6-oxoheptanedioate + CoA
EC 2.3.1.117
Pathway Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 1/3.
Subunit Homotrimer.
Subcellular location Cytoplasm.
Similarity Belongs to the transferase hexapeptide repeat family.

Keywords [?]

Acyltransferase
Amino-acid biosynthesis
Cytoplasm
Diaminopimelate biosynthesis
Lysine biosynthesis
Repeat
Transferase

Gene Ontology [?]

GO:0008666; Molecular function: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity.
GO:0019877; Biological process: diaminopimelate biosynthetic process.
GO:0009089; Biological process: lysine biosynthetic process via diaminopimelate.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00132; Hexapep; 5;
TIGRFAMs TIGR00965; DapD; 1;
PROSITE PS00101; HEXAPEP_TRANSFERASES; 1;

Features [?]

From: DAPD_UNKP (P56220)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     104     104       Substrate     R  
BINDING     141     141       Substrate     D  

Additional information [?]

Size range 271-289 amino acids
Related rules None
Fusion None
Comments There is a second family of DapD (see MF_02122).


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