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Annotation rule MF_00835 |
Accession | MF_00835 |
Dates | 27-JUN-2011 (Created) 18-NOV-2019 (Last updated, Version 6) |
Name | BioC |
Scope | Bacteria |
Templates | P12999 (BIOC_ECOLI); P36571 (BIOC_SERMA): [Recover all] |
Triggered by |
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Protein name |
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Gene name |
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Function | Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. |
Catalytic activity | RHEA:17105: malonyl-[ACP] + S-adenosyl-L-methionine = malonyl-[ACP] methyl ester + S-adenosyl-L-homocysteine
EC 2.1.1.197 |
Pathway | Cofactor biosynthesis; biotin biosynthesis. |
Similarity | Belongs to the methyltransferase superfamily. |
PROSITE | PS00599; AA_TRANSFER_CLASS_2; 1; |
Pfam | PF08241; Methyltransf_11; 1; |
PF08242; Methyltransf_12; 1; | |
TIGRFAMs | TIGR02072; BioC; 1; |
Size range | 245-350 amino acids |
Related rules | None |
Fusion | Nter: MF_01260 (BioH); Cter: MF_00336 (BioD), <Unknown> |