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Annotation rule MF_00842 |
General rule information
[?]
Accession |
MF_00842 |
Dates |
25-APR-2019 (Created) 18-NOV-2019 (Last updated, Version 4) |
Scope |
Bacteria; Proteobacteria |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
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Full=Outer membrane protein A;
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AltName:
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Full=Outer membrane porin A;
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Function |
With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. |
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella> or <OC:Klebsiella> or <OC:Erwinia>
Function |
Required for conjugation with F-type plasmids; probably serves as the mating receptor on recipient cells. |
end case
Subunit |
Monomer and homodimer. |
Subcellular location |
Cell outer membrane; Multi-pass membrane protein. |
Domain |
The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins. |
Similarity |
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family. |
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella> or <OC:Klebsiella> or <OC:Erwinia>
end case
case <FTTag:Disulfide>
end case
GO:0009279; Cellular component: cell outer membrane.
GO:0034220; Biological process: ion transmembrane transport.
GO:0015288; Molecular function: porin activity.
General |
Signal; -; 0-1; trigger=yes; |
From: OMPA_ECOLI (P0A910) |
Key
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From
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To
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Description
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Tag
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Condition
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|
FTGroup
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TRANSMEM
|
|
27
|
|
37
|
|
Beta stranded
|
|
|
|
|
|
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TRANSMEM
|
|
55
|
|
66
|
|
Beta stranded
|
|
|
|
|
|
|
TRANSMEM
|
|
70
|
|
78
|
|
Beta stranded
|
|
|
|
|
|
|
TRANSMEM
|
|
96
|
|
107
|
|
Beta stranded
|
|
|
|
|
|
|
TRANSMEM
|
|
112
|
|
120
|
|
Beta stranded
|
|
|
|
|
|
|
TRANSMEM
|
|
142
|
|
151
|
|
Beta stranded
|
|
|
|
|
|
|
TRANSMEM
|
|
156
|
|
163
|
|
Beta stranded
|
|
|
|
|
|
|
TRANSMEM
|
|
182
|
|
190
|
|
Beta stranded
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|
|
|
|
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SITE
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73
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|
73
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Part of salt bridge gating mechanism
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E
|
|
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SITE
|
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159
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159
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Part of salt bridge gating mechanism
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|
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R
|
|
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DISULFID (Optional)
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311
|
|
323
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Disulfide
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C-x*-C
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Additional information
[?]
Size range |
320-390 amino acids |
Related rules |
None |
Fusion |
None |