HAMAP rule MF_00868

General rule information [?]

Accession	MF_00868
Dates	10-JUN-2022 (Created) 13-JAN-2023 (Last updated, Version 4)
Name	Cds1
Scope(s)	Bacteria
Template(s)	O69652 (CDS1_MYCTU); A5U908 (CDS1_MYCTA); [ Recover all ]
Triggered by	HAMAP; MF_00868 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	CDS1
Protein name	RecName: Full=L-cysteine desulfhydrase Cds1; EC=4.4.1.1;
Gene name	Name=cds1;

Comments [?]

case <OC:Actinomycetota>
FUNCTION	A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress).
else
FUNCTION	A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.
end case
CATALYTIC ACTIVITY	Reaction=H2O + L-cysteine = H(+) + hydrogen sulfide + NH4(+) + pyruvate; Xref=Rhea:RHEA:24931, ChEBI:CHEBI:15361, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:28938, ChEBI:CHEBI:29919, ChEBI:CHEBI:35235; EC=4.4.1.1; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:24932;
case <FT:1>
COFACTOR	Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
end case
SIMILARITY	Belongs to the cysteine synthase/cystathionine beta- synthase family. Cds1 subfamily.

Keywords [?]

Gene Ontology [?]

GO:0005737; Cellular component:cytoplasm

GO:0030170; Molecular function:pyridoxal phosphate binding

GO:0019450; Biological process:L-cysteine catabolic process to pyruvate

Cross-references [?]

Pfam	PF00291; PALP; 1;

Features [?]

From: CDS1_MYCTU (O69652)

Key

From

Description

Tag

Condition

FTGroup

MOD_RES

/note="N6-(pyridoxal phosphate)lysine"

Additional information [?]