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Annotation rule MF_00868 |
Accession | MF_00868 |
Dates | 10-JUN-2022 (Created) 13-JAN-2023 (Last updated, Version 4) |
Name | Cds1 |
Scope | Bacteria |
Templates | O69652 (CDS1_MYCTU); A5U908 (CDS1_MYCTA): [Recover all] |
Triggered by |
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Function | A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress). |
Function | A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism. |
Catalytic activity | RHEA:24931: H2O + L-cysteine = H(+) + hydrogen sulfide + NH4(+) + pyruvate
EC 4.4.1.1 PhysiologicalDirection=left-to-right (RHEA:24932) |
Cofactor | pyridoxal 5'-phosphate |
Similarity | Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily. |
Pfam | PF00291; PALP; 1; |
From: CDS1_MYCTU (O69652) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
MOD_RES | 67 | 67 | N6-(pyridoxal phosphate)lysine | K |
Size range | 340-440 amino acids |
Related rules | None |
Fusion | None |