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Annotation rule MF_00868 |
General rule information
[?]
Accession |
MF_00868 |
Dates |
10-JUN-2022 (Created) 17-JUN-2022 (Last updated, Version 2) |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=L-cysteine desulfhydrase Cds1;
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EC 4.4.1.1;
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case <OC:Actinobacteria>
Function |
A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress). |
else
Function |
A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism. |
end case
Catalytic activity |
RHEA:24931: H2O + L-cysteine = H(+) + hydrogen sulfide + NH4(+) + pyruvate
EC 4.4.1.1
PhysiologicalDirection=left-to-right
(RHEA:24932)
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case <FT:1>
end case
Similarity |
Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily. |
case <FT:1>
end case
GO:0005737; Cellular component: cytoplasm.
GO:0030170; Molecular function: pyridoxal phosphate binding.
GO:0019450; Biological process: L-cysteine catabolic process to pyruvate.
From: CDS1_MYCTU (O69652) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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MOD_RES
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67
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67
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N6-(pyridoxal phosphate)lysine
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K
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Additional information
[?]
Size range |
340-440 amino acids |
Related rules |
None |
Fusion |
None |