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Annotation rule MF_00905 |
Accession | MF_00905 |
Dates | 17-AUG-2011 (Created) 19-NOV-2019 (Last updated, Version 8) |
Name | cAMP_phosphodiest_CpdA |
Scope | Bacteria |
Templates | P9WP65 (CPDA_MYCTU); P0AEW4 (CPDA_ECOLI); D4P095 (CPDA_PSEAI); Q8YLG0 (CPDA_NOSS1); P44685 (CPDA_HAEIN): [Recover all] |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. |
Catalytic activity | RHEA:25277: 3',5'-cyclic AMP + H2O = AMP + H(+)
EC 3.1.4.53 |
Cofactor | a metal cation Note: Binds 2 metal cations per subunit. |
Similarity | Belongs to the cAMP phosphodiesterase class-III family. |
Pfam | PF00149; Metallophos; 1; |
From: CPDA_MYCTU (P9WP65) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
NP_BIND | 97 | 98 | cAMP | N-H | ||||||||
METAL | 21 | 21 | Metal cation 1 | D | ||||||||
METAL | 23 | 23 | Metal cation 1 | H | ||||||||
METAL | 63 | 63 | Metal cation 1 | D | ||||||||
METAL | 63 | 63 | Metal cation 2 | D | ||||||||
METAL | 97 | 97 | Metal cation 2 | N | ||||||||
METAL | 169 | 169 | Metal cation 2 | H | ||||||||
METAL | 207 | 207 | Metal cation 2 | H | ||||||||
METAL | 209 | 209 | Metal cation 1 | H | ||||||||
BINDING | 23 | 23 | cAMP | H | ||||||||
BINDING | 63 | 63 | cAMP | D | ||||||||
BINDING | 209 | 209 | cAMP | H |
Size range | 233-340 amino acids |
Related rules | None |
Fusion | None |