HAMAP rule MF_00926

Accession	MF_00926
Dates	9-OCT-2012 (Created) 1-JUN-2023 (Last updated, Version 6)

Name

DksA

Scope

Bacteria

Template

P0ABS1 (DKSA_ECOLI)

Triggered by

HAMAP; MF_00926 (Get profile general information and statistics)

Identifier

DKSA

Protein name

RecName: Full=RNA polymerase-binding transcription factor DksA;

Gene name

dksA

Function

Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

Function

Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

Subunit	Interacts directly with the RNA polymerase.
Subcellular location	Cytoplasm.
Similarity	Belongs to the DksA family.

Cytoplasm
Metal-binding
Zinc
Zinc-finger

GO:0008270; Molecular function: zinc ion binding.
GO:0010468; Biological process: regulation of gene expression.
GO:0005737; Cellular component: cytoplasm.

PROSITE	PS01102; ZF_DKSA_1; 1;
	PS51128; ZF_DKSA_2; 1; trigger=PRU00510;
Pfam	PF01258; zf-dskA_traR; 1;
PRINTS	PR00618; DKSAZNFINGER; 1;
NCBIfam	TIGR02420; dksA; 1;

General

Coiled_coil; -; 0-unlimited; trigger=yes;

From: DKSA_ECOLI (P0ABS1)

Key

From

To

Description

Tag

Condition

FTGroup

BINDING (Optional)

114

114

/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105

C

1

BINDING (Optional)

117

117

/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105

C

1

BINDING (Optional)

135

135

/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105

C

1

BINDING (Optional)

138

138

/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105

C

1

Size range	115-200 amino acids
Related rules	None
Fusion	None

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