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HAMAP rule MF_00926

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General rule information [?]

Accession MF_00926
Dates 9-OCT-2012 (Created)
1-JUN-2023 (Last updated, Version 6)
Name DksA
Scope(s) Bacteria
Template(s) P0ABS1 (DKSA_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00926 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier DKSA
Protein name RecName: Full=RNA polymerase-binding transcription factor DksA;
Gene name Name=dksA;

Comments [?]

case <OC:Gammaproteobacteria>
FUNCTIONTranscription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.
else
FUNCTIONTranscription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.
end case
SUBUNITInteracts directly with the RNA polymerase.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the DksA family.

Keywords [?]


Gene Ontology [?]

GO:0008270; Molecular function:zinc ion binding
GO:0010468; Biological process:regulation of gene expression
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

PROSITE PS01102; ZF_DKSA_1; 1;
PROSITE PS51128; ZF_DKSA_2; 1;
Pfam PF01258; zf-dskA_traR; 1;
PRINTS PR00618; DKSAZNFINGER; 1;
NCBIfam TIGR02420; dksA; 1;
General Coiled_coil; -; 0-unlimited;

Features [?]

From: DKSA_ECOLI (P0ABS1)
Key From To Description Tag Condition FTGroup
BINDING 114 114 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
C 1
BINDING 117 117 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
C 1
BINDING 135 135 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
C 1
BINDING 138 138 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
C 1

Additional information [?]

Size range 115-200 amino acids
Related rules None
Fusion Nter: None Cter: None



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