HAMAP rule MF_00926
General rule information
[?]
Accession | MF_00926 |
Dates | 9-OCT-2012 (Created)
1-JUN-2023 (Last updated, Version 6) |
Name | DksA |
Scope(s) |
Bacteria |
Template(s) | P0ABS1 (DKSA_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_00926 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier | DKSA |
Protein name | RecName: Full=RNA polymerase-binding transcription factor DksA; |
Gene name | Name=dksA; |
Comments
[?]
case <OC:Gammaproteobacteria> | |
FUNCTION | Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. |
else | |
FUNCTION | Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. |
end case | |
SUBUNIT | Interacts directly with the RNA polymerase. |
SUBCELLULAR LOCATION | Cytoplasm. |
SIMILARITY | Belongs to the DksA family. |
Keywords
[?]
Gene Ontology
[?]
GO:0008270; Molecular function:zinc ion binding |
GO:0010468; Biological process:regulation of gene expression |
GO:0005737; Cellular component:cytoplasm |
Cross-references
[?]
PROSITE | PS01102; ZF_DKSA_1; 1; |
PROSITE | PS51128; ZF_DKSA_2; 1; |
Pfam | PF01258; zf-dskA_traR; 1; |
PRINTS | PR00618; DKSAZNFINGER; 1; |
NCBIfam | TIGR02420; dksA; 1; |
General | Coiled_coil; -; 0-unlimited; |
Features
[?]
From: DKSA_ECOLI (P0ABS1) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 114 | 114 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
BINDING | 117 | 117 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
BINDING | 135 | 135 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
BINDING | 138 | 138 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 |
Additional information
[?]
Size range | 115-200 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |