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Annotation rule MF_00934
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General rule information [?]

Accession MF_00934
Dates 17-JAN-2013 (Created)
19-NOV-2019 (Last updated, Version 6)
Name 23SrRNA_methyltr_J
Scope
Bacteria
Template P37634 (RLMJ_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RLMJ
Protein name
RecName: Full=Ribosomal RNA large subunit methyltransferase J;
EC 2.1.1.266;
AltName: Full=23S rRNA (adenine(2030)-N6)-methyltransferase;
AltName: Full=23S rRNA m6A2030 methyltransferase;
Gene name
rlmJ

Comments [?]

Function Specifically methylates the adenine in position 2030 of 23S rRNA.
Catalytic activity RHEA:43736: adenosine(2030) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(2030) in 23S rRNA + S-adenosyl-L-homocysteine
EC 2.1.1.266
Subunit Monomer.
Similarity Belongs to the RlmJ family.

Keywords [?]


Gene Ontology [?]

GO:0036307; Molecular function: 23S rRNA (adenine(2030)-N(6))-methyltransferase activity.
GO:0003723; Molecular function: RNA binding.
GO:0070475; Biological process: rRNA base methylation.

Cross-references [?]

PROSITE PS00092; N6_MTASE; 2;
Pfam PF04378; DUF519; 1;

Features [?]

From: RLMJ_ECOLI (P37634)
Key     From     To       Description   Tag   Condition   FTGroup
REGION (Optional)     143     144       S-adenosyl-L-methionine binding     [DNE]-[GAS]  
ACT_SITE     164     164       Proton acceptor     D  
BINDING     19     19       S-adenosyl-L-methionine     H  
BINDING     42     42       S-adenosyl-L-methionine; via carbonyl oxygen     [HYFN]  
BINDING     100     100       S-adenosyl-L-methionine     S  
BINDING     118     118       S-adenosyl-L-methionine     [ED]  
BINDING     164     164       S-adenosyl-L-methionine     D  
SITE     4     4       Interaction with substrate rRNA     Y  

Additional information [?]

Size range 240-362 amino acids
Related rules None
Fusion None