HAMAP rule MF_00935

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00935
Accession	MF_00935
Dates	18-JAN-2013 (Created) 03-SEP-2024 (Last updated, Version 10)
Name	AlaDH_arch
Scope(s)	Archaea Bacteria
Template(s)	O28608; [ Recover all ]
Triggered by	HAMAP; MF_00935 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	ALADH
case <OC:Archaea>
Protein name	RecName: Full=Alanine dehydrogenase; Short=AlaDH; EC=1.4.1.1;
Gene name	Name=ala;
else case <OC:Bacteria>
Protein name	RecName: Full=Putative alanine dehydrogenase; Short=AlaDH; EC=1.4.1.1;
end case

Comments [?]

FUNCTION	Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
CATALYTIC ACTIVITY	Reaction=L-alanine + NAD(+) + H2O = pyruvate + NH4(+) + NADH + H(+); Xref=Rhea:RHEA:18405, ChEBI:CHEBI:15361, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:28938, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:57972; EC=1.4.1.1;
SIMILARITY	Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.

Keywords [?]

Gene Ontology [?]

GO:0000286; Molecular function:alanine dehydrogenase activity

GO:0051287; Molecular function:NAD binding

GO:0006522; Biological process:alanine metabolic process

Cross-references [?]

Features [?]

From: ALADH_ARCFU (O28608)

Key

From

Description

Tag

Condition

FTGroup

BINDING

135

136