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Annotation rule MF_00941
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General rule information [?]

Accession MF_00941
Dates 7-FEB-2013 (Created)
19-NOV-2019 (Last updated, Version 5)
Name GDPMH_gmm
Scope
Bacteria; Enterobacteriaceae
Template P32056 (GMM_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
GMM
Protein name
RecName: Full=GDP-mannose mannosyl hydrolase;
Short=GDPMH;
EC 3.6.1.-;
Gene name
gmm

Comments [?]

Function Hydrolyzes GDP-mannose.
Catalytic activity RHEA:28102: GDP-alpha-D-mannose + H2O = D-mannose + GDP + H(+)
case <FTGroup:1>
Cofactor Mg(2+)
Note: Binds 1 Mg(2+) ion per subunit.
end case
Subunit Homodimer.
Similarity Belongs to the Nudix hydrolase family.

Keywords [?]

Hydrolase
case <FTGroup:1>
Magnesium
Metal-binding
end case

Gene Ontology [?]

GO:0008727; Molecular function: GDP-mannose mannosyl hydrolase activity.
case <FTGroup:1>
GO:0000287; Molecular function: magnesium ion binding.
end case

Cross-references [?]

PROSITE PS51462; NUDIX; 1; trigger=PRU00794;
PS00893; NUDIX_BOX; 1;
Pfam PF00293; NUDIX; 1;
PIRSF PIRSF037599; GDPMH; 1;

Features [?]

From: GMM_ECOLI (P32056)
Key     From     To       Description   Tag   Condition   FTGroup
REGION (Optional)     2     3       Substrate binding     F-L  
METAL     49     49       Magnesium; via carbonyl oxygen     G   1
METAL     69     69       Magnesium     E   1
METAL     122     122       Magnesium     Q   1
BINDING (Optional)     8     8       Substrate     F  
BINDING (Optional)     36     36       Substrate     R  

Additional information [?]

Size range 130-184 amino acids
Related rules None
Fusion None


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