HAMAP rule MF_00941
General rule information
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Accession | MF_00941 |
Dates | 7-FEB-2013 (Created) 19-NOV-2022 (Last updated, Version 8) |
Name | GDPMH_gmm |
Scope | Bacteria; Enterobacteriaceae |
Template | P32056 (GMM_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Hydrolyzes GDP-mannose. |
Catalytic activity | RHEA:28102: GDP-alpha-D-mannose + H2O = D-mannose + GDP + H(+) |
case <FTGroup:1>
Cofactor | Mg(2+) Note: Binds 1 Mg(2+) ion per subunit. |
end case
Subunit | Homodimer. |
Similarity | Belongs to the Nudix hydrolase family. |
Keywords
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case <FTGroup:1>
end case
Gene Ontology
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GO:0008727; Molecular function: GDP-mannose mannosyl hydrolase activity.
case <FTGroup:1>
GO:0000287; Molecular function: magnesium ion binding.
end case
Cross-references
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PROSITE | PS51462; NUDIX; 1; trigger=PRU00794; |
PS00893; NUDIX_BOX; 1; | |
Pfam | PF00293; NUDIX; 1; |
PIRSF | PIRSF037599; GDPMH; 1; |
Features
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From: GMM_ECOLI (P32056) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING (Optional) | 2 | 3 | /ligand="substrate | F-L | ||||||||
BINDING | 49 | 49 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420 | G | 1 | |||||||
BINDING | 69 | 69 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420 | E | 1 | |||||||
BINDING | 122 | 122 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420 | Q | 1 | |||||||
BINDING (Optional) | 8 | 8 | /ligand="substrate | F | ||||||||
BINDING (Optional) | 36 | 36 | /ligand="substrate | R |
Additional information
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Size range | 130-184 amino acids |
Related rules | None |
Fusion | None |