HAMAP rule MF_00967

General rule information [?]

Accession	MF_00967
Dates	25-JUN-2013 (Created) 26-JAN-2023 (Last updated, Version 6)

Name	DEAD_helicase_SrmB

Scope

Bacteria; Pseudomonadota

Template

P21507 (SRMB_ECOLI)

Triggered by

HAMAP; MF_00967 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

SRMB

Protein name

RecName:		Full=ATP-dependent RNA helicase SrmB;
		EC 3.6.4.13;

Gene name

srmB

Comments [?]

Function	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
Catalytic activity	RHEA:13065: ATP + H2O = ADP + H(+) + phosphate EC 3.6.4.13
Subunit	Interacts with the 50S ribosomal subunit.
Subcellular location	Cytoplasm.
Similarity	Belongs to the DEAD box helicase family. SrmB subfamily.

Keywords [?]

ATP-binding
Cytoplasm
Helicase
Hydrolase
Nucleotide-binding
Ribosome biogenesis

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0003724; Molecular function: RNA helicase activity.
GO:0000027; Biological process: ribosomal large subunit assembly.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE	PS00039; DEAD_ATP_HELICASE; 1;
	PS51192; HELICASE_ATP_BIND_1; 1; trigger=PRU00541;
	PS51194; HELICASE_CTER; 1; trigger=PRU00542;
	PS51195; Q_MOTIF; 1; trigger=PRU00552;
Pfam	PF00270; DEAD; 1;
	PF00271; Helicase_C; 1;

Additional information [?]

Size range	400-470 amino acids
Related rules	None
Fusion	None

View rule in raw text format (no links)