HAMAP rule MF_00967
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00967 |
| Accession | MF_00967 |
| Dates | 25-JUN-2013 (Created)
03-SEP-2024 (Last updated, Version 8) |
| Name | DEAD_helicase_SrmB |
| Scope(s) |
Bacteria Pseudomonadota |
| Template(s) | P21507; [ Recover all ] |
| Triggered by |
HAMAP; MF_00967 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | SRMB |
| Protein name | RecName: Full=ATP-dependent RNA helicase SrmB; EC=3.6.4.13; |
| Gene name | Name=srmB; |
Comments
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| FUNCTION | DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity. |
| CATALYTIC ACTIVITY | Reaction=ATP + H2O = ADP + phosphate + H(+); Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13; |
| SUBUNIT | Interacts with the 50S ribosomal subunit. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the DEAD box helicase family. SrmB subfamily. |
Keywords
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Gene Ontology
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| GO:0005524; Molecular function:ATP binding |
| GO:0003724; Molecular function:RNA helicase activity |
| GO:0000027; Biological process:ribosomal large subunit assembly |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| PROSITE | PS00039; DEAD_ATP_HELICASE; 1; |
| PROSITE | PS51192; HELICASE_ATP_BIND_1; 1; |
| PROSITE | PS51194; HELICASE_CTER; 1; |
| PROSITE | PS51195; Q_MOTIF; 1; |
| Pfam | PF00270; DEAD; 1; |
| Pfam | PF00271; Helicase_C; 1; |
Features
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Additional information
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| Size range | 400-470 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |