HAMAP rule MF_00968
General rule information
[?]
| PURL | https://purl.expasy.org/hamap/rule/MF_00968 |
| Accession | MF_00968 |
| Dates | 28-JUN-2013 (Created)
3-SEP-2024 (Last updated, Version 6) |
| Name | DEAD_helicase_RhlE |
| Scope(s) |
Bacteria |
| Template(s) | P25888 (RHLE_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00968 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Identifier | RHLE |
| Protein name | RecName: Full=ATP-dependent RNA helicase RhlE; EC=3.6.4.13; |
| Gene name | Name=rhlE; |
Comments
[?]
| FUNCTION | DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. |
| CATALYTIC ACTIVITY | Reaction=ATP + H2O = ADP + phosphate + H(+); Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13; |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the DEAD box helicase family. RhlE subfamily. |
Keywords
[?]
Gene Ontology
[?]
| GO:0005524; Molecular function:ATP binding |
| GO:0003724; Molecular function:RNA helicase activity |
| GO:0042254; Biological process:ribosome biogenesis |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
[?]
| PROSITE | PS00039; DEAD_ATP_HELICASE; 1; |
| PROSITE | PS51192; HELICASE_ATP_BIND_1; 1; |
| PROSITE | PS51194; HELICASE_CTER; 1; |
| PROSITE | PS51195; Q_MOTIF; 1; |
| Pfam | PF00270; DEAD; 1; |
| Pfam | PF00271; Helicase_C; 1; |
Features
[?]
Additional information
[?]
| Size range | 397-650 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |