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HAMAP rule MF_00968

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General rule information [?]

PURL https://purl.expasy.org/hamap/rule/MF_00968
Accession MF_00968
Dates 28-JUN-2013 (Created)
3-SEP-2024 (Last updated, Version 6)
Name DEAD_helicase_RhlE
Scope(s) Bacteria
Template(s) P25888 (RHLE_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00968 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RHLE
Protein name RecName: Full=ATP-dependent RNA helicase RhlE;
                 EC=3.6.4.13;
Gene name Name=rhlE;

Comments [?]

FUNCTIONDEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.
CATALYTIC ACTIVITY Reaction=ATP + H2O = ADP + phosphate + H(+); Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the DEAD box helicase family. RhlE subfamily.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0003724; Molecular function:RNA helicase activity
GO:0042254; Biological process:ribosome biogenesis
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

PROSITE PS00039; DEAD_ATP_HELICASE; 1;
PROSITE PS51192; HELICASE_ATP_BIND_1; 1;
PROSITE PS51194; HELICASE_CTER; 1;
PROSITE PS51195; Q_MOTIF; 1;
Pfam PF00270; DEAD; 1;
Pfam PF00271; Helicase_C; 1;

Features [?]


Additional information [?]

Size range 397-650 amino acids
Related rules None
Fusion Nter: None Cter: None



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