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HAMAP rule MF_00983

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General rule information [?]

Accession MF_00983
Dates 7-JAN-2014 (Created)
19-NOV-2019 (Last updated, Version 4)
Name PriA
Template P17888 (PRIA_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

case not <Feature:PS51192> and not <Feature:PS51194>
Protein name
RecName: Full=Probable primosomal protein N';
EC 3.6.4.-;
AltName: Full=ATP-dependent helicase PriA;
Protein name
RecName: Full=Primosomal protein N';
EC 3.6.4.-;
AltName: Full=ATP-dependent helicase PriA;
end case
Gene name

Comments [?]

Function Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
Subunit Component of the primosome.
Similarity Belongs to the helicase family. PriA subfamily.

Keywords [?]

case <FTTag:zinc>
end case

Gene Ontology [?]

GO:0003678; Molecular function: DNA helicase activity.
GO:0005524; Molecular function: ATP binding.
GO:0003677; Molecular function: DNA binding.
case <FTTag:zinc>
GO:0008270; Molecular function: zinc ion binding.
end case
GO:0006268; Biological process: DNA unwinding involved in DNA replication.
GO:1990077; Cellular component: primosome complex.

Cross-references [?]

PROSITE PS51192; HELICASE_ATP_BIND_1; 0-1; trigger=PRU00541;
PS51194; HELICASE_CTER; 0-1; trigger=PRU00542;
Pfam PF00270; DEAD; 1;
PF00271; Helicase_C; 1;
TIGRFAMs TIGR00595; priA; 1;

Features [?]

From: PRIA_ECOLI (P17888)
Key     From     To       Description   Tag   Condition   FTGroup
ZN_FING     436     448       C4-type   zinc   C-x(2)-C-x(5)-C-x(2)-C  
ZN_FING     463     479       C4-type   zinc   C-x(2)-C-x(7,10)-C-x(2)-C  

Additional information [?]

Size range 535-950 amino acids
Related rules None
Fusion None