HAMAP rule MF_00983

General rule information [?]

Accession	MF_00983
Dates	7-JAN-2014 (Created) 19-NOV-2019 (Last updated, Version 4)

Name

PriA

Scope

Bacteria

Template

P17888 (PRIA_ECOLI)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

PRIA

case not <Feature:PS51192> and not <Feature:PS51194>

Protein name

RecName:		Full=Probable primosomal protein N';
		EC 3.6.4.-;
AltName:		Full=ATP-dependent helicase PriA;

else

Protein name

RecName:		Full=Primosomal protein N';
		EC 3.6.4.-;
AltName:		Full=ATP-dependent helicase PriA;

end case

Gene name

priA

Comments [?]

Function	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
Subunit	Component of the primosome.
Similarity	Belongs to the helicase family. PriA subfamily.

Keywords [?]

case <FTTag:zinc>

end case

Gene Ontology [?]

GO:0003678; Molecular function: DNA helicase activity.
GO:0005524; Molecular function: ATP binding.
GO:0003677; Molecular function: DNA binding.

case <FTTag:zinc>

GO:0008270; Molecular function: zinc ion binding.

end case

GO:0006268; Biological process: DNA unwinding involved in DNA replication.
GO:1990077; Cellular component: primosome complex.

Cross-references [?]

PROSITE	PS51192; HELICASE_ATP_BIND_1; 0-1; trigger=PRU00541;
	PS51194; HELICASE_CTER; 0-1; trigger=PRU00542;
Pfam	PF00270; DEAD; 1;
	PF00271; Helicase_C; 1;
TIGRFAMs	TIGR00595; priA; 1;

Features [?]

From: PRIA_ECOLI (P17888)

Key From To Description Tag Condition FTGroup

ZN_FING 436 448 C4-type zinc C-x(2)-C-x(5)-C-x(2)-C

ZN_FING 463 479 C4-type zinc C-x(2)-C-x(7,10)-C-x(2)-C

Additional information [?]