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Annotation rule MF_00992 |
Accession | MF_00992 |
Dates | 14-FEB-2014 (Created) 3-APR-2020 (Last updated, Version 10) |
Name | MqnC |
Scope | Bacteria
Archaea |
Templates | Q9K864 (MQNC_BACHD); Q9XAP2 (MQNC_STRCO): [Recover all] |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). |
Catalytic activity | RHEA:33083: dehypoxanthine futalosine + S-adenosyl-L-methionine = 5'-deoxyadenosine + cyclic dehypoxanthinylfutalosinate + H(+) + L-methionine
EC 1.21.98.1 |
Cofactor | [4Fe-4S] cluster Note: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. |
Pathway | Quinol/quinone metabolism; menaquinone biosynthesis. |
Similarity | Belongs to the radical SAM superfamily. MqnC family. |
Pfam | PF04055; Radical_SAM; 1; |
TIGRFAMs | TIGR03699; mena_SCO4550; 1; |
TIGR00423; TIGR00423; 1; | |
PIRSF | PIRSF004762; CHP00423; 1; |
PROSITE | PS51918; RADICAL_SAM; 1; trigger=PRU01266; |
From: MQNC_BACHD (Q9K864) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
METAL | 64 | 64 | Iron-sulfur (4Fe-4S-S-AdoMet) | C | 1 | |||||||
METAL | 68 | 68 | Iron-sulfur (4Fe-4S-S-AdoMet) | C | 1 | |||||||
METAL | 71 | 71 | Iron-sulfur (4Fe-4S-S-AdoMet) | C | 1 |
Size range | 325-500 amino acids |
Related rules | None |
Fusion | None |