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Annotation rule MF_00994 |
Accession | MF_00994 |
Dates | 14-FEB-2014 (Created) 19-NOV-2019 (Last updated, Version 4) |
Name | LPS_assembly_LapB |
Scope | Bacteria; Proteobacteria |
Template | P0AB58 (LAPB_ECOLI) |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane. |
Subcellular location | Cell inner membrane; Single-pass membrane protein; Cytoplasmic side. |
Similarity | Belongs to the LapB family. |
PROSITE | PS50005; TPR; 1; |
PS50293; TPR_REGION; 1; | |
Pfam | PF07719; TPR_2; 1; |
PF13176; TPR_7; 1; | |
PF00515; TPR_1; 1; |
REP | Repeat_TPR; TPR; 2-7; trigger=yes; |
From: LAPB_ECOLI (P0AB58) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
TRANSMEM | 1 | 20 | Helical | |||||||||
TOPO_DOM | 21 | Cter | Cytoplasmic | |||||||||
METAL | 357 | 357 | Iron | C | 1 | |||||||
METAL | 360 | 360 | Iron | C | 1 | |||||||
METAL | 371 | 371 | Iron | C | 1 | |||||||
METAL | 374 | 374 | Iron | C | 1 |
Size range | 350-430 amino acids |
Related rules | None |
Fusion | None |